ArticleInternational ophthalmology2019
Assessment of superficial retinal microvascular density in healthy myopia.
Article in International ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Axial Length-Associated Structural and Microvascular Retinal Changes in Myopia: A Combined OCT and OCTA Analysis.Translational vision science & technology · 2026Observational
- Retinal and Choroidal Microvasculature at Different Myopia Severities: A Systematic Review and Meta-Analysis.Ophthalmology science · 2026Review
- The Significance of OCTA in Studying Vessel Density and Retinal Thickness in Individuals with Myopia.Medicina (Kaunas, Lithuania) · 2025Article
- The Effect of Partial Sleep Deprivation on Retinal Microvasculature in Myopia With Different Axial Lengths.Investigative ophthalmology & visual science · 2025Article
- Axial length, more than aging, decreases the thickness and superficial vessel density of retinal nerve fiber layer in non-glaucomatous eyes.International ophthalmology · 2024Article
- Compartmental analysis of retinal vascular parameters and thickness in myopic eyes using SS-OCTA.Frontiers in medicine · 2024Article
- Molecular mechanism of hypoxia and alpha-ketoglutaric acid on collagen expression in scleral fibroblasts.International journal of ophthalmology · 2024Article
- Evaluation of childhood developingWorld journal of clinical cases · 2023Article
- The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula-An OCTA Study.Medicina (Kaunas, Lithuania) · 2023Article
- Retinal microvascular and microstructural alterations in the diagnosis of meibomian gland dysfunction in severely obese population: a new approach.International journal of ophthalmology · 2023Article
- Prospective clinical study of retinal microvascular alteration after ICL implantation.Frontiers in cell and developmental biology · 2023Article
- Effect of shape deprivation on retinal thickness in myopic mice using an OCT method.Frontiers in neuroscience · 2023Article
- Changes of retinal vessel density in low to moderate myopic eyes with orthokeratology evaluated by optical coherence tomography angiography.International journal of ophthalmology · 2023Article
- Diagnostic ability of superficial vascular density measured by optical coherence tomography angiography to differentiate high myopic eyes from eyes with primary open angle glaucoma.Indian journal of ophthalmology · 2022Observational
- Macular Vessel Density Changes in Young Adults With High Myopia: A Longitudinal Study.Frontiers in medicine · 2021Article
- Vessel Density and Retinal Thickness from Optical Coherence Tomography Angiography as New Indexes in Adolescent Myopia.Journal of ophthalmology · 2021Article
- The Effect of Axial Length on Macular Vascular Density in Eyes with High Myopia.Romanian journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo evaluate retinal microvasculature in healthy myopia and investigate the correlation between microvascular density and ocular factors.
methodsA total of 174 eyes from 174 healthy Korean subjects were included. The eyes were divided into four groups according to refraction: emmetropia [21 eyes, - 1.00 D ≤ mean spherical equivalent (MSE) < + 0.75 D], mild myopia (32 eyes, - 3.00 D ≤ MSE < - 1.00 D), moderate myopia (76 eyes, - 6.00 D ≤ MSE < - 3.00 D), and high myopia (45 eyes, MSE < - 6.00 D). Images of retinal vasculature in parapapillary and parafoveal area were obtained using optical coherence tomography angiography. Superficial retinal microvascular density was measured for correlation analysis with ocular parameters.
resultsHigh myopia was found to have a lower superficial parapapillary microvascular density compared with the other groups in total parapapillary area, and in sectors of nasal and inferonasal (all p ≤ 0.001). The superficial parapapillary microvascular density showed a negative correlation with axial length (AL) and intraocular pressure (IOP) (β = - 0.479, p = 0.008 and β = - 0.160, p = 0.048, respectively), and a positive correlation with parapapillary retinal nerve fiber layer (RNFL) thickness (β = 0.140, p < 0.001). However, there was no significant difference in superficial parafoveal microvascular density among all groups (p > 0.05).
conclusionsThis study reveals that superficial parapapillary microvascular density is lower in high myopia and has correlation with AL, IOP, and parapapillary RNFL thickness. It also indicates that superficial parafoveal microvascular density tends to be unaffected by healthy myopia. These retinal microvascular alterations may facilitate understanding the pathogenesis of glaucomatous optic nerve damage in high myopia.
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Registered trials
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