ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2019
Determinants of time to institutionalisation and related healthcare and societal costs in a community-based cohort of patients with Alzheimer's disease dementia.
Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Activities of Daily Living and Associated Costs in the Most Widespread Neurodegenerative Diseases: A Systematic Review.Clinical interventions in aging · 2020Pooled it
- Utilization and Lifetime Costs of Formal Care for Alzheimer's Disease Dementia in Sweden.PharmacoEconomics · 2026Article
- Assessing technologies in dementia care: A conceptual health-economic model.Journal of Alzheimer's disease : JAD · 2026Article
- Mortality and institutionalization of patients with dementia treated in primary care: influence of neuropsychiatric symptoms (NeDEM project).BMC geriatrics · 2025Observational
- Association between comorbidity indices and nursing home admission in patients with Alzheimer's disease: a longitudinal observational study using the MEMORA cohort.BMC geriatrics · 2025Observational
- Effects of the TovertafelFrontiers in neurology · 2024Article
- Implementation and dissemination of home- and community-based interventions for informal caregivers of people living with dementia: a systematic scoping review.Implementation science : IS · 2023Article
- Amyloid Positron Emission Tomography and Subsequent Health Care Use Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia.JAMA neurology · 2023Article
- Cost-effectiveness models for Alzheimer's disease and related dementias: IPECAD modeling workshop cross-comparison challenge.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Carer-reported measures for a dementia registry: A systematic scoping review and a qualitative study.Australasian journal on ageing · 2023Article
- Development of multivariable prediction models for institutionalization and mortality in the full spectrum of Alzheimer's disease.Alzheimer's research & therapy · 2022Article
- The Humanistic and Economic Burden of Alzheimer's Disease.Neurology and therapy · 2022Review
- Health economic modeling for Alzheimer's disease: Expert perspectives.Alzheimer's & dementia (New York, N. Y.) · 2022Article
- Eldercare services for people with and without a dementia diagnosis: an analysis of Swedish registry data.BMC health services research · 2021Article
- Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status, Physical Performance, Cognitive Function, and Blood Pressure in Prefrail and Frail Older Adults.Frontiers in medicine · 2021Article
- Time Investment for Program Implementation to Manage Neuropsychiatric Symptoms: An Observational Longitudinal Study in In-Home and Residential Care Settings.Journal of Alzheimer's disease reports · 2020Article
- Time from diagnosis to institutionalization and death in people with dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2020Article
- Time from dementia diagnosis to nursing-home admission and death among persons with dementia: A multistate survival analysis.PloS one · 2020Article
- Prediction of poor clinical outcome in vascular cognitive impairment: TRACE-VCI study.Alzheimer's & dementia (Amsterdam, Netherlands) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectivesTo examine the costs of caring for community-dwelling patients with Alzheimer's disease (AD) dementia in relation to the time to institutionalisation.
methodsGERAS was a prospective, non-interventional cohort study in community-dwelling patients with AD dementia and their caregivers in three European countries. Using identified factors associated with time to institutionalisation, models were developed to estimate the time to institutionalisation for all patients. Estimates of monthly total societal costs, patient healthcare costs and total patient costs (healthcare and social care together) prior to institutionalisation were developed as a function of the time to institutionalisation.
resultsOf the 1495 patients assessed at baseline, 307 (20.5%) were institutionalised over 36 months. Disease severity at baseline [based on Mini-Mental State Examination (MMSE) scores] was associated with risk of being institutionalised during follow up (p < 0.001). Having a non-spousal informal caregiver was associated with a faster time to institutionalisation (944 fewer days versus having a spousal caregiver), as was each one-point worsening in baseline score of MMSE, instrumental activities of daily living and behavioural disturbance (67, 50 and 30 fewer days, respectively). Total societal costs, total patient costs and, to a lesser extent, patient healthcare-only costs were associated with time to institutionalisation. In the 5 years pre-institutionalisation, monthly total societal costs increased by more than £1000 (€1166 equivalent for 2010) from £1900 to £3160 and monthly total patient costs almost doubled from £770 to £1529.
conclusionsTotal societal costs and total patient costs rise steeply as community-dwelling patients with AD dementia approach institutionalisation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.