Evidence map›Paper›PMID 30178076›Full record

ReviewInfection2019

Vancomycin-resistant enterococci (VRE): a reason to isolate?

Maria J G T Vehreschild, Miriam Haverkamp, Lena M Biehl, Sebastian Lemmen, Gerd Fätkenheuer

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04624464 (Assessing the Impact of Antimicrobial Exposure and Infection Control Measures on the Spread of Vancomycin-resistant Enterococcus Faecium), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04624464 unknown statusnot on this map

Assessing the Impact of Antimicrobial Exposure and Infection Control Measures on the Spread of Vancomycin-resistant Enterococcus Faecium (VREf) - A Prospective Study

Typeobservational_patient_registrySponsorUniversity Hospital of CologneRan2019 to 2020Enrolled170ConditionsVRE Infection, Antibiotic Resistant InfectionArmsRectal swabs - microbiological analysis, Examination of patient room
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Genomic epidemiology ofJournal of clinical microbiology · 2026
    Observational
  3. Article
  4. Article
  5. Article
  6. Vancomycin-ResistantAntibiotics (Basel, Switzerland) · 2025
    Review
  7. Spread of the novel vancomycin-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Observational
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Co-Existence of Oxazolidinone Resistance GenesAntibiotics (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Maria J G T VehreschildDepartment I of Internal Medicine, University Hospital of Cologne, 50924, Cologne, Germany.
Miriam HaverkampZentralbereich für Krankenhaushygiene und Infektiologie, Uniklinik Aachen, Aachen, Germany.
Lena M BiehlDepartment I of Internal Medicine, University Hospital of Cologne, 50924, Cologne, Germany.
Sebastian LemmenZentralbereich für Krankenhaushygiene und Infektiologie, Uniklinik Aachen, Aachen, Germany.
Gerd FätkenheuerDepartment I of Internal Medicine, University Hospital of Cologne, 50924, Cologne, Germany. g.faetkenheuer@uni-koeln.de.
German Center for Infection Research · DEUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, an increase in invasive VRE infections has been reported worldwide, including Germany. The most common gene encoding resistance to glycopeptides is VanA, but predominant VanB clones are emerging. Although neither the incidence rates nor the exact routes of nosocomial transmission of VRE are well established, screening and strict infection control measures, e.g. single room contact isolation, use of personal protective clothing by hospital staff and intensified surface disinfection for colonized individuals, are implemented in many hospitals. At the same time, the impact of VRE infection on mortality remains unclear, with current evidence being weak and contradictory. In this short review, we aim to give an overview on the current basis of evidence on the clinical effectiveness of infection control measures intended to prevent transmission of VRE and to put these findings into a larger perspective that takes further factors, e.g. VRE-associated mortality and impact on patient care, into account.

Indexed as

Vancomycin ResistanceGram-Positive Bacterial InfectionsHumansInfection ControlPatient CareVancomycin-Resistant EnterococciEnterococciInfection controlIsolationScreeningVancomycinVancomycin-resistant

Identifiers

PMID30178076
OpenAlexW2890477840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.