Evidence map›Paper›PMID 30178075›Full record

ReviewIrish journal of medical science2019

Oral antiplatelets in primary and secondary prevention of myocardial infarction: a review.

Rajkumar Doshi, Abhishek Vadher, Priyam Mithawala, Priyank Shah

Abstract readReview
PubMed Publisher
In one paragraph

Review in Irish journal of medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Who needs acetylsalicylic acid? Some order after many studies.European heart journal supplements : journal of the European Society of Cardiology · 2020
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Rajkumar DoshiDepartment of Internal Medicine, Renown Regional Medical Centre, University of Nevada Reno School of Medicine, 1155 Mill St, W-11, Reno, NV, 89502, USA. rdoshi@med.unr.edu.ORCID http://orcid.org/0000-0002-5618-2750
Abhishek VadherDepartment of Cardiology, North Shore University Hospital, Hofstra Northwell School of Medicine, Manhasset, NY, USA.
Priyam MithawalaDepartment of Pharmacy, Presbyterian College School of Pharmacy, Clinton, SC, USA.
Priyank ShahDepartment of Cardiology, Phoebe Putney Memorial Hospital, Albany, GA, USA.
North Shore University Hospital · USPhoebe Putney Memorial Hospital · USPresbyterian College · USUniversity of Nevada, Reno · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are a number of guidelines and articles available for the use of oral antiplatelets for primary and secondary prevention of myocardial infarction (MI). Antiplatelet medications inhibit platelet activation, aggregation, and other pathways eventually inhibiting clot formation. Aspirin and clopidogrel have been the mainstay in the management of acute coronary syndrome for about a decade. We have discussed the role of aspirin, clopidogrel, ticagrelor, and prasugrel which are the most commonly used oral antiplatelet medications in the current era. We have also considered the role of newer thrombin inhibitor vorapaxar, and dual antiplatelet therapy. In this review paper, we have summarized the continuing controversy about the use of oral antiplatelet therapy and their role in primary as well as secondary prevention of MI by describing results from major clinical trials. The safety and the efficacy of the above medications have been reviewed and described in this paper.

Indexed as

AgedAspirinHumansMyocardial InfarctionPlatelet Aggregation InhibitorsSecondary PreventionAspirinPlatelet Aggregation InhibitorsAspirinOral antiplateletsP2Y12 inhibitorsPrevention

Identifiers

PMID30178075
OpenAlexW2891224391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.