Evidence map›Paper›PMID 30177973›Full record

ArticleReactive oxygen species (Apex, N.C.)2018

Graphene Quantum Dots Protect against Copper Redox-Mediated Free Radical Generation and Cardiac Cell Injury.

Y Robert Li, Arben Santo, Hong Zhu, Zhenquan Jia, Michael A Trush

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reactive oxygen species (Apex, N.C.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Y Robert LiDepartment of Pharmacology, Campbell University Medical School, Buies Creek, NC 27506, USA.
Arben SantoDepartment of Pathology, EVCOM, Virginia Tech CRC, Blacksburg, VA 24060, USA.
Hong ZhuDepartment of Physiology and Pathophysiology, Campbell University Medical School, Buies Creek, NC 27506, USA.
Zhenquan JiaDepartment of Pharmacology, Campbell University Medical School, Buies Creek, NC 27506, USA.
Michael A TrushDepartment of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Campbell University · USJohns Hopkins University · USVirginia Tech · USVirginia Tech - Wake Forest University School of Biomedical Engineering & Sciences · US

Funding

Cruciferous Dithiolethiones for Chronic Heart Failure: Signaling MechanismsR15CA192936 · NCI · CAMPBELL UNIVERSITY · PI LI, YUNBO · 2014 to 2014
$469k
Novel Carbon Nanodots against Vascular InflammationR15HL129212 · NHLBI · UNIVERSITY OF NORTH CAROLINA GREENSBORO · PI JIA, ZHENQUAN · 2016 to 2016
$455k
Activating Multiorgan Antioxidative Gene Network for Treating SepsisR15GM124652 · NIGMS · CAMPBELL UNIVERSITY · PI ZHU, HONG · 2018 to 2018
$447k
NCI NIH HHS R15 CA192936NHLBI NIH HHS R15 HL129212NIGMS NIH HHS R15 GM124652
6 · The paper itself

Abstract

In this work, we investigated the effects of graphene quantum dots (GQDs) on copper redox-mediated free radical generation and cell injury. Using electron paramagnetic resonance (EPR) spectrometry in conjunction with 5,5-dimethyl-1-pyrroline

Indexed as

Copper redoxElectron paramagnetic resonanceGraphene quantum dotsHuman cardiomyocytesHydrogen peroxideHydroquinoneHydroxyl radicalNanotechnologyOxygen polarographySpin-trapping

Identifiers

PMID30177973
PMCPMC6112819
OpenAlexW2887065087

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.