ArticleJournal of development economics2018
The impact of packaging and messaging on adherence to malaria treatment: Evidence from a randomized controlled trial in Uganda.
Article in Journal of development economics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Adherence to anti-malarials among patients diagnosed with malaria in East Africa: a systematic review and meta-analysis.Malaria journal · 2025Pooled it
- Pooled it
- Behavioral Interventions Improve Mailed Colorectal Cancer Screening Among Overdue Patients in a Randomized Trial.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026Trial
- Adherence to treatment with artemether-lumefantrine or amodiaquine-artesunate for uncomplicated malaria in children in Sierra Leone: a randomized trial.Malaria journal · 2018Trial
- Impact of health education intervention on the patients' adherence to malaria artemisinin-based combination therapy in Kamuli District, Uganda.Malaria journal · 2025Article
- Adapting malaria indicator surveys to investigate treatment adherence: a pilot study on Bioko Island, Equatorial Guinea.Malaria journal · 2024Article
- Community education training to optimize the use of artemisinin-based combination therapy in Kamuli District, Uganda.BMC public health · 2024Article
- Field testing of user-friendly perennial malaria chemoprevention packaging in Benin, Côte d'Ivoire and Mozambique.Malaria journal · 2024Observational
- Medication adherence framework: A population-based pharmacokinetic approach and its application in antimalarial treatment assessments.CPT: pharmacometrics & systems pharmacology · 2024Article
- Factors influencing patients' adherence to malaria artemisinin-based combination therapy in Kamuli District, Uganda.Malaria journal · 2024Article
- A broader perspective on the economics of malaria prevention and the potential impact of SARS-CoV-2.Nature communications · 2022Article
- Strengthening therapeutic adherence and pharmacovigilance to antimalarial treatment in Manaus, Brazil: a multicomponent strategy using mHealth.Malaria journal · 2022Article
- God is in the rain: The impact of rainfall-induced early social distancing on COVID-19 outbreaks.Journal of health economics · 2022Article
- Adherence to Dihydroartemisinin-Piperaquine Treatment among Patients with Uncomplicated Malaria in Northern Ghana.Journal of tropical medicine · 2019Article
- Patients' adherence to artemisinin-based combination therapy and healthcare workers' perception and practice in Savannakhet province, Lao PDR.Tropical medicine and health · 2018Article
- Success of Big Infectious Disease Reimbursement Policy in China.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite substantial public and private costs of non-adherence to infectious disease treatments, patients often do not finish their medication. We explore adherence to medication for malaria, a major cause of morbidity and health system costs in Africa. We conducted a randomized trial in Uganda testing specialized packaging and messaging, designed to increase antimalarial adherence. We find that stickers with short, targeted messages on the packaging increase adherence by 9% and reduce untaken pills by 29%. However, the currently used method of boosting adherence through costly, specialized packaging with pictorial instructions had no significant impacts relative to the standard control package. We develop a theoretical framework of the adherence decision, highlighting the role of symptoms, beliefs about being cured, and beliefs about drug effectiveness to help interpret our results. Patients whose symptoms resolve sooner are substantially less likely to adhere, and the sticker interventions have the strongest impact among these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.