Evidence map›Paper›PMID 30177751›Full record

ArticleScientific reports2018

Class II histone deacetylases require P/Q-type Ca

Francisco J Urbano, Verónica Bisagno, Susan Mahaffey, Sang-Hun Lee, Edgar Garcia-Rill

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Francisco J UrbanoCenter for Translational Neuroscience, Department Neurobiology & Dev. Sci., University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Verónica BisagnoININFA, CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina.
Susan MahaffeyCenter for Translational Neuroscience, Department Neurobiology & Dev. Sci., University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Sang-Hun LeeCenter for Translational Neuroscience, Department Neurobiology & Dev. Sci., University of Arkansas for Medical Sciences, Little Rock, AR, USA.ORCID 0000-0001-8880-2785
Edgar Garcia-RillCenter for Translational Neuroscience, Department Neurobiology & Dev. Sci., University of Arkansas for Medical Sciences, Little Rock, AR, USA. garciarilledgar@uams.edu.
University of Arkansas for Medical Sciences · USConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

Telemedicine CoreP30GM110702 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI GARCIA-RILL, EDGAR E. · 2014 to 2018
$6.1M
NIGMS NIH HHS P30 GM110702
6 · The paper itself

Abstract

Epigenetic mechanisms (i.e., histone post-translational modification and DNA methylation) play a role in regulation of gene expression. The pedunculopontine nucleus (PPN), part of the reticular activating system, manifests intrinsic gamma oscillations generated by voltage-dependent, high threshold N- and P/Q-type Ca

Indexed as

AnimalsAnimals, NewbornBenzamidesBenzenesulfonamidesBenzylaminesCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium Channels, P-TypeCalcium Channels, Q-TypeGamma RhythmGene Expression RegulationHistone Deacetylase InhibitorsHistone DeacetylasesHydroxamic AcidsIndolesMicrotomyNeuronsBenzamidesBenzenesulfonamidesBenzylaminesCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium Channels, P-TypeCalcium Channels, Q-TypeentinostatHistone Deacetylase InhibitorsHistone DeacetylasesHydroxamic AcidsIndolesKN 93MC1568PyridinesPyrrolesSulfonamidestrichostatin Atubastatin A

Identifiers

PMID30177751
PMCPMC6120910
OpenAlexW2889488863

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.