Evidence map›Paper›PMID 30177749›Full record

ArticleScientific reports2018

GABAergic and cholinergic modulation of repetition suppression in inferior temporal cortex.

Pradeep Kuravi, Rufin Vogels

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pradeep KuraviLaboratorium voor Neuro- en Psychofysiologie, Department of Neurosciences, KU Leuven, Leuven, Belgium.
Rufin VogelsLaboratorium voor Neuro- en Psychofysiologie, Department of Neurosciences, KU Leuven, Leuven, Belgium. rufin.vogels@kuleuven.be.
VIB-KU Leuven Center for Brain & Disease Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurons in many brain areas of different species reduce their response when a stimulus is repeated. Such adaptation or repetition suppression is prevalent in inferior temporal (IT) cortex. The mechanisms underlying repetition suppression in IT are still poorly understood. Studies in rodents and in-vitro experiments suggest that acetylcholine and GABA can contribute to repetition suppression by interacting with fatigue-related or local adaptation mechanisms. Here, we examined the contribution of cholinergic and GABAergic mechanisms to repetition suppression in macaque IT, using an adaptation paradigm in which familiar images were presented successively with a short interstimulus interval. We found that intracortical local injections of acetylcholine and of the GABA

Indexed as

AcetylcholineAction PotentialsAdaptation, PhysiologicalAlpha RhythmAnimalsBeta RhythmCholinergic AgentsElectrodes, ImplantedFemaleGABA AgentsGamma RhythmInjections, IntraventricularMacaca mulattaMaleNeuronsPattern Recognition, VisualAcetylcholineCholinergic AgentsGABA AgentsgabazinePyridazines

Identifiers

PMID30177749
PMCPMC6120963
OpenAlexW2889421198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.