Evidence map›Paper›PMID 30177714›Full record

ArticleScientific reports2018

Blood Pressure Control and Cardiovascular Outcomes: Real-world Implications of the 2017 ACC/AHA Hypertension Guideline.

Ji Hyun Lee, Sun-Hwa Kim, Si-Hyuck Kang, Jun Hwan Cho, Youngjin Cho, Il-Young Oh, Chang-Hwan Yoon, Hae-Young Lee, Tae-Jin Youn, In-Ho Chae and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Doxazosin GITS (gastrointestinal therapeutic system) is an actor to consider in the control of hypertension. A narrative review.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  6. Vasomotor symptoms of menopause, sympathetic activity, and blood pressure in postmenopausal females.American journal of physiology. Heart and circulatory physiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ji Hyun LeeDepartment of Cardiology, Wonju Medical College, Yonsei University, Wonju, Korea.ORCID 0000-0002-7162-1248
Sun-Hwa KimCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
Si-Hyuck KangCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea. eandp303@snu.ac.kr.ORCID 0000-0003-4755-6367
Jun Hwan ChoCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
Youngjin ChoCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
Il-Young OhCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
Chang-Hwan YoonCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
Hae-Young LeeDepartment of Internal Medicine, Seoul National University, Seoul, Korea.
Tae-Jin YounCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
In-Ho ChaeCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.
Cheol-Ho KimCardiovascular Center, Seoul National University Bundang Hospital, Seongnam-si, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension guideline lowered the threshold defining hypertension and treatment target from 140/90 mmHg to 130/80 mmHg. We compared the 2017 ACC/AHA guideline and the Eighth Joint National Committee (JNC8) report with regard to the current status of hypertension using the Korean National Health and Nutrition Examination Survey. The association between blood pressure (BP) control and long-term major cardiovascular outcomes (MACEs) was analyzed using the Korea National Health Insurance Service cohort. In the cross-sectional study with 15,784 adults, the prevalence of hypertension was expected to be 49.2 ± 0.6% based on the definition suggested by the 2017 ACC/AHA guideline versus 30.4 ± 0.6% based on the JNC8 report. In a longitudinal analysis with 373,800 hypertensive adults for the median follow-up periods of 11.0 years, the adults meeting the target goal BP goal of 2017 ACC/AHA guideline were associated with 21% reduced risk of MACEs compared with adults, not meeting 2017 ACC/AHA BP goal but meeting JNC8 target goal. In conclusion, substantial increase of prevalence of hypertension is expected by the 2017 ACC/AHA guideline. This study also suggests endorsing the aggressive approach would lead to an improvement in cardiovascular care.

Indexed as

AgedAntihypertensive AgentsBlood PressureBlood Pressure Monitoring, AmbulatoryCross-Sectional StudiesFemaleHealth SurveysHumansHypertensionMaleMiddle AgedPractice Guidelines as TopicPrevalenceRepublic of KoreaSurvival AnalysisTreatment OutcomeAntihypertensive Agents

Identifiers

PMID30177714
PMCPMC6120944

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.