Evidence map›Paper›PMID 30177686›Full record

ArticleNature communications2018

Single reach plans in dorsal premotor cortex during a two-target task.

Brian M Dekleva, Konrad P Kording, Lee E Miller

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 86 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Motor working memory.Trends in cognitive sciences · 2026
    Review
  5. Article
  6. Article
  7. Uncertainty Shapes Neural Dynamics in Motor Cortex During Reaching.bioRxiv : the preprint server for biology · 2025
    Article
  8. Online Movements Reflect Ongoing Deliberation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  9. Differential Beta and Gamma Activity Modulation during Unimanual and Bimanual Motor Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Prospection of Potential Actions during Visual Working Memory Starts Early, Is Flexible, and Predicts Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. An abstract categorical decision code in dorsal premotor cortex.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 3 countries.

Brian M DeklevaDepartment of Biomedical Engineering, Northwestern University, 633 Clark St, Evanston, Chicago, IL, 60208, USA.
Konrad P KordingDepartment of Biomedical Engineering, Northwestern University, 633 Clark St, Evanston, Chicago, IL, 60208, USA.ORCID http://orcid.org/0000-0001-8408-4499
Lee E MillerDepartment of Biomedical Engineering, Northwestern University, 633 Clark St, Evanston, Chicago, IL, 60208, USA. lm@northwestern.edu.ORCID http://orcid.org/0000-0001-8675-7140
Northwestern University · US

Funding

The representation of uncertainty in the sensorimotor systemR01NS074044 · NINDS · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI KORDING, KONRAD P., MILLER, LEE · 2011 to 2015
$1.6M
Motor Cortical Function During Motor Learning with a Brain-Machine InterfaceF31NS092356 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PERICH, MATTHEW GEORGE · 2015 to 2017
$93k
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) F31NS092356U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS074044
6 · The paper itself

Abstract

In many situations, we are faced with multiple potential actions, but must wait for more information before knowing which to perform. Movement scientists have long asked whether in these delayed-response situations the brain plans both potential movements simultaneously, or if it simply chooses one and then switches later if necessary. To answer this question, we used simultaneously recorded activity from populations of neurons in macaque dorsal premotor cortex to track moment-by-moment deliberation between two potential reach targets. We found that the neural activity only ever indicated a single-reach plan (with some targets favored more than others), and that initial plans often predicted the monkeys' behavior on both Free-Choice trials and incorrect Cued trials. Our results suggest that premotor cortex plans only one option at a time, and that decisions are strongly influenced by the initial response to the available set of movement options.

Indexed as

CuesAnimalsBehavior, AnimalChoice BehaviorDecision MakingMacaca mulattaMotor CortexMovementNeurons

Identifiers

PMID30177686
PMCPMC6120937
OpenAlexW2889102173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.