Evidence map›Paper›PMID 30177636›Full record

ArticleInternational journal of molecular sciences2018

Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro.

Chun-Ming Shih, Chien-Yu Huang, Kuo-Hsien Wang, Chun-Yao Huang, Po-Li Wei, Yu-Jia Chang, Chi-Kun Hsieh, Kuan-Ting Liu, Ai-Wei Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Aberrations in Lipid Expression and Metabolism in Psoriasis.International journal of molecular sciences · 2021
    Review
  11. Oxidized Lipids and Lipoprotein Dysfunction in Psoriasis.Journal of psoriasis and psoriatic arthritis · 2020
    Article
  12. Review
  13. Article
  14. Caveolin as a Universal Target in Dermatology.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chun-Ming ShihDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. cmshih53@tmu.edu.tw.
Chien-Yu HuangDepartment of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. cyh@tmu.edu.tw.
Kuo-Hsien WangDepartment of Dermatology, Taipei Medical University Hospital, Taipei 11031, Taiwan. 162014@h.tmu.edu.tw.
Chun-Yao HuangDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. cyhuang@tmu.edu.tw.
Po-Li WeiDepartment of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. poliwei@tmu.edu.tw.
Yu-Jia ChangDepartment of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. r5424012@tmu.edu.tw.
Chi-Kun HsiehDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. faceeric0302@yahoo.com.tw.
Kuan-Ting LiuDepartment of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. jack841023yes@gmail.com.
Ai-Wei LeeDepartment of Anatomy and Cell Biology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan. ammielee@tmu.edu.tw.
Taipei Medical University · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin disease. Even though scientists predict that abnormalities in lipid metabolism play an important role in the pathogenesis of psoriasis, the actual underlying mechanisms are still unclear. Therefore, understanding the possible relationship between mechanisms of the occurrence of psoriasis and dyslipidemia is an important issue that may lead to the development of effective therapies. Under this principle, we investigated the influences of hyperlipidemia in imiquimod (IMQ)-induced psoriasis-like B6.129S2-

Indexed as

AnimalsCell LineCholesterolHumansInterleukin-23Lipoproteins, LDLMicePsoriasisScavenger Receptors, Class ETranscriptional ActivationCholesterolInterleukin-23Lipoproteins, LDLoxidized low density lipoproteinScavenger Receptors, Class ELOX-1oxLDLpsoriasis

Identifiers

PMID30177636
PMCPMC6163499
OpenAlexW2889500830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.