Evidence map›Paper›PMID 30177603›Full record

ArticleMolecules (Basel, Switzerland)2018

Antinociceptive Effects of Cardamonin in Mice: Possible Involvement of TRPV₁, Glutamate, and Opioid Receptors.

Chung Pui Ping, Tengku Azam Shah Tengku Mohamad, Muhammad Nadeem Akhtar, Enoch Kumar Perimal, Ahmad Akira, Daud Ahmad Israf Ali, Mohd Roslan Sulaiman

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chung Pui PingDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Selangor, Serdang 43400, Malaysia. puiping.chung@gmail.com.
Tengku Azam Shah Tengku MohamadDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Selangor, Serdang 43400, Malaysia. azamshah@upm.edu.my.
Muhammad Nadeem AkhtarLaboratory of Natural Products, Institute of Bioscience, Universiti Putra Malaysia, Selangor, Serdang 43400, Malaysia. nadeemupm@gmail.com.
Enoch Kumar PerimalDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Selangor, Serdang 43400, Malaysia. enoch@upm.edu.my.ORCID 0000-0003-2666-7340
Ahmad AkiraDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Selangor, Serdang 43400, Malaysia. ahmadakira@upm.edu.my.
Daud Ahmad Israf AliDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Selangor, Serdang 43400, Malaysia. daudaia@upm.edu.my.
Mohd Roslan SulaimanDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia Selangor, Serdang 43400, Malaysia. mrs@upm.edu.my.
Universiti Putra Malaysia · MYUniversiti Malaysia Pahang Al-Sultan Abdullah · MY

Funding

Universiti Putra Malaysia GP-IBT/2013/9409600
6 · The paper itself

Abstract

Pain is one of the most common cause for hospital visits. It plays an important role in inflammation and serves as a warning sign to avoid further injury. Analgesics are used to manage pain and provide comfort to patients. However, prolonged usage of pain treatments like opioids and NSAIDs are accompanied with undesirable side effects. Therefore, research to identify novel compounds that produce analgesia with lesser side effects are necessary. The present study investigated the antinociceptive potentials of a natural compound, cardamonin, isolated from

Indexed as

Administration, OralAnalgesicsAnimalsChalconesDisease Models, AnimalDose-Response Relationship, DrugGlutamic AcidInjections, IntraperitonealMicePainPlant ExtractsReceptors, OpioidTRPV Cation ChannelsZingiberaceaeAnalgesicscardamoninChalconesGlutamic AcidPlant ExtractsReceptors, OpioidTRPV1 protein, mouseTRPV Cation ChannelsantinociceptivecardamoninglutamateopioidTRPV1

Identifiers

PMID30177603
PMCPMC6225316
OpenAlexW2889343095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.