ArticleNutrients2018
Levels of Growth Factors and IgA in the Colostrum of Women from Burundi and Italy.
Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The Breast Milk Immunoglobulinome.Nutrients · 2021Pooled it
- Oropharyngeal administration of colostrum for preventing necrotizing enterocolitis and late-onset sepsis in preterm infants with gestational age ≤ 32 weeks: a pilot single-center randomized controlled trial.International breastfeeding journal · 2021Trial
- Pilot Study of Growth Factors in Colostrum: How Delivery Mode and Maternal Health Impact IGF-1, EGF, NGF, and TGF-β Levels in Polish Women.Nutrients · 2025Article
- The primiparous IgA and IL-5 colostrum concentration based on maternal factor: corroborate the inflammation pathways to IgA colostrum synthesis.AJOG global reports · 2025Article
- Article
- An Exploration of Pepino (Foods (Basel, Switzerland) · 2022Article
- Association between Maternal Characteristics and Immune Factors TGF-β1, TGF-β2, and IgA in Colostrum: An Exploratory Study in Japan.Nutrients · 2022Article
- Gestational Diabetes Mellitus Changes Human Colostrum Immune Composition.Frontiers in immunology · 2022Article
- The effect of antenatal care on colostrum avoidance in pastoralists: The case of Afar, Northeast Ethiopia.Global pediatric health · 2021Article
- Does Caesarean Section or Preterm Delivery Influence TGF-β2 Concentrations in Human Colostrum?Nutrients · 2020Article
- Review
- Human Breast Milk: Bioactive Components, from Stem Cells to Health Outcomes.Current nutrition reports · 2020Review
- Impact of Holder pasteurization on immunological properties of human breast milk over the first year of lactation.Pediatric research · 2020Article
- Review
- Breastfeeding and Human Lactation.Nutrients · 2019Article
- Effects of Probiotic Supplementation on TGF-β1, TGF-β2, and IgA Levels in the Milk of Japanese Women: An Open-Label Pilot Study.Frontiers in nutrition · 2019Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colostrum is produced in the first days postpartum. It is a known source of immune mediators for a newborn within the first week of life. Although it is still unclear if colostrum composition varies between populations, recent data suggest differences. Hepatocyte growth factor (HGF); transforming growth factor-β (TGF-β) 1, 2, and 3; and immunoglobulin A (IgA) are key immunological components of colostrum that stimulate neonatal gastrointestinal and immune system development. We aimed to investigate the differences in the concentration between immune markers in the colostrum of mothers living in Burundi and Italy, and to identify the factors associated with differences. In this cross-sectional birth cohort study, a total of 99 colostrum samples from Burundian (
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