ArticleParasites & vectors2018
Transmission of Rickettsia raoultii and Rickettsia massiliae DNA by Dermacentor reticulatus and Rhipicephalus sanguineus (s.l.) ticks during artificial feeding.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Diversity and Occurrence of Tick-Borne Pathogens in Small Ruminants and Their Ticks in Sardinia: Implications for Animal Health and Zoonotic Risk.Veterinary sciences · 2026Article
- Rickettsia massiliae and its public health significance across Palearctic and Oriental regions: a scoping review.Infectious diseases of poverty · 2026Article
- Discovery of mCMV280: An Oral Ectoparasiticide in the Isoxazoline Class with Reduced Mammalian Brain Exposure.Journal of medicinal chemistry · 2026Article
- First detection of one of the tick-borne lymphadenopathy (TIBOLA) etiological agent in ticks from a highly frequented sub-urban forest near Paris, France.PLOS global public health · 2026Article
- The Rhipicephalus sanguineus group: updated list of species, geographical distribution, and vector competence.Parasites & vectors · 2024Review
- Molecular Detection and Characterization of Rickettsia Species in Ixodid Ticks from Selected Regions of Namibia.Microorganisms · 2024Article
- Detection of Rickettsia raoultii in Vermipsylla alakurt-Like Fleas of Sheep in Northwestern China.Acta parasitologica · 2024Article
- Molecular Evidence ofMicroorganisms · 2023Article
- Genetic diversity of vector-borne pathogens in ixodid ticks infesting dogs from Pakistan with notes on Ehrlichia canis, Rickettsia raoultii and Dirofilaria immitis detection.Parasites & vectors · 2023Article
- Bacterial Agents Detected in 418 Ticks Removed from Humans during 2014-2021, France.Emerging infectious diseases · 2023Review
- Visual closed dumbbell-mediated isothermal amplification (CDA) for on-site detection of Rickettsia raoultii.PLoS neglected tropical diseases · 2022Article
- Rickettsia massiliae circulation in sheep and attached Rhipicephalus sanguineus in Central Portugal.Tropical animal health and production · 2022Article
- Molecular Survey and Spatial Distribution ofPathogens (Basel, Switzerland) · 2022Article
- Evaluating Transmission Paths for Three DifferentMicroorganisms · 2021Article
- Amblyomma hebraeum is the predominant tick species on goats in the Mnisi Community Area of Mpumalanga Province South Africa and is co-infected with Ehrlichia ruminantium and Rickettsia africae.Parasites & vectors · 2020Article
- "Tekenscanner": a novel smartphone application for companion animal owners and veterinarians to engage in tick and tick-borne pathogen surveillance in the Netherlands.Parasites & vectors · 2019Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTick-borne rickettsial pathogens are emerging worldwide and pose an increased health risk to both humans and animals. A plethora of rickettsial species has been identified in ticks recovered from human and animal patients. However, the detection of rickettsial DNA in ticks does not necessarily mean that these ticks can act as vectors for these pathogens. Here, we used artificial feeding of ticks to confirm transmission of Rickettsia massiliae and Rickettsia raoultii by Rhipicephalus sanguineus (sensu lato) and Dermacentor reticulatus ticks, respectively. The speed of transmission was also determined.
methodsAn artificial feeding system based on silicone membranes were used to feed adult R. sanguineus (s.l.) and D. reticulatus ticks. Blood samples from in vitro feeding units were analysed for the presence of rickettsial DNA using PCR and reverse line blot hybridisation.
resultsThe attachment rate of R. sanguineus (s.l.) ticks were 40.4% at 8 h post-application, increasing to 70.2% at 72 h. Rickettsia massiliae was detected in blood samples collected 8 h after the R. sanguineus (s.l.) ticks were placed into the in vitro feeding units. D. reticulatus ticks were pre-fed on sheep and subsequently transferred to the in vitro feeding system. The attachment rate was 29.1 % at 24 h post-application, increasing to 43.6 % at 96 h. Rickettsia raoultii was detected in blood collected 24 h after D. reticulatus was placed into the feeding units.
conclusionsRhipicephalus sanguineus (s.l.) and D. reticulatus ticks are vectors of R. massiliae and R. raoultii, respectively. The transmission of R. massiliae as early as 8 h after tick attachment emphasises the importance of removing ticks as soon as possible to minimise transmission. This study highlights the relevance of in vitro feeding systems to provide insight into the vectorial capacity of ticks and the dynamics of tick-borne pathogen transmission.
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