Evidence map›Paper›PMID 30176909›Full record

ArticleBMC research notes2018

Research proposal: inflammation and oxidative stress in coronary artery bypass surgery graft: comparison between diabetic and non-diabetic patients.

Ana Catarina Romano E Silva, Glauber Monteiro Dias, Jorge José de Carvalho, Andrea De Lorenzo, Daniel Arthur Barata Kasal

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Glycated Haemoglobin Levels and Its Effect on Outcomes in Cardiac Surgery.Brazilian journal of cardiovascular surgery · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ana Catarina Romano E SilvaNational Institute of Cardiology, Ministry of Health, Rua das Laranjeiras No. 374, Rio de Janeiro, RJ, 22240-006, Brazil.
Glauber Monteiro DiasNational Institute of Cardiology, Ministry of Health, Rua das Laranjeiras No. 374, Rio de Janeiro, RJ, 22240-006, Brazil.
Jorge José de CarvalhoBiomedical Center, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Andrea De LorenzoNational Institute of Cardiology, Ministry of Health, Rua das Laranjeiras No. 374, Rio de Janeiro, RJ, 22240-006, Brazil.
Daniel Arthur Barata KasalNational Institute of Cardiology, Ministry of Health, Rua das Laranjeiras No. 374, Rio de Janeiro, RJ, 22240-006, Brazil. dabkasal@gmail.com.
Ministério da Saúde · BRUniversidade do Estado do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus patients (DM) have more severe progression of atherosclerotic disease than non-diabetic (NDM) individuals. In situ inflammation and oxidative stress are key points in the pathophysiology of atherosclerosis, a concept largely based on animal model research. There are few studies comparing inflammation and oxidative stress parameters in medium-sized arteries between DM and NDM patients. A fragment of the internal mammary artery used in coronary artery bypass grafting (CABG) will be employed for this purpose

objectiveTo assess the expression of inflammatory markers tumor necrosis factor-α, transforming growth factor-β1, nuclear factor kappa B, the enzymes superoxide dismutase, and catalase in the vascular wall of the arterial graft used in CABG, comparing DM and NDM patients

resultsThe present study will add information to the vascular degenerative processes occurring in diabetic patients.

Indexed as

Coronary Artery BypassInflammationOxidative StressAdolescentAdultCoronary Artery DiseaseCross-Sectional StudiesDiabetes ComplicationsDiabetes MellitusHumansMaleResearch DesignCoronary artery bypass graftingDiabetes mellitusInflammationOxidative stress

Identifiers

PMID30176909
PMCPMC6122454
OpenAlexW2889472894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.