ArticleVirology journal2018
Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus.
Article in Virology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 88 citations in OpenAlex.
- Review
- Protein-Derived Signal Peptides Induced by Agrobacterium Infection Promote the Secretion of Recombinant Proteins in Nicotiana benthamiana.Plant biotechnology journal · 2026Article
- Positive-Strand RNA Viruses Induce LTR Retrotransposon Transcription and Extrachromosomal Circular DNA Generation in Plants.International journal of molecular sciences · 2025Article
- Key regulatory genes in sugar beet's defense against curly top virus identified by network analysis and qRT-PCR.Biochemistry and biophysics reports · 2025Article
- Cold suppresses virus accumulation and alters the host transcriptomic response in the turnip mosaic virus-Arabidopsis halleri system.Plant & cell physiology · 2025Article
- Transcriptomics in solanaceous crop improvement: advances and opportunities.Frontiers in plant science · 2025Review
- Transcriptional and epigenetic changes during tomato yellow leaf curl virus infection in tomato.BMC plant biology · 2023Article
- Transcriptome Sequencing and WGCNA Reveal Key Genes in Response to Leaf Blight in Poplar.International journal of molecular sciences · 2023Article
- Molecular insights into the responses of barley to yellow mosaic disease through transcriptome analysis.BMC plant biology · 2023Article
- vsiRNA18 derived from tobacco curly shoot virus can regulate virus infection in Nicotiana benthamiana.Molecular plant pathology · 2023Article
- Review
- Transcriptome mapping related genes encoding PR1 protein involved in necrotic symptoms to soybean mosaic virus infection.Molecular breeding : new strategies in plant improvement · 2023Article
- Transcriptomic alterations in the sweet orange vasculature correlate with growth repression induced by a variant of citrus tristeza virus.Frontiers in microbiology · 2023Article
- Article
- Transcriptome analyses unveiled differential regulation of AGO and DCL genes by pepino mosaic virus strains.Molecular plant pathology · 2022Article
- Integrated transcriptomic and transgenic analyses reveal potential mechanisms of poplar resistance to Alternaria alternata infection.BMC plant biology · 2022Article
- Effects of the Noncoding Subgenomic RNA of Red Clover Necrotic Mosaic Virus in Virus Infection.Journal of virology · 2022Article
- The interplay of plant hormonal pathways and geminiviral proteins: partners in disease development.Virus genes · 2022Review
- RNA sequencing reveals transcriptomic changes in tobacco (Nicotiana tabacum) following NtCPS2 knockdown.BMC genomics · 2021Article
- Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTobacco curly shoot virus (TbCSV) is a monopartite begomovirus associated with betasatellite (Tobacco curly shoot betasatellite, TbCSB), which causes serious leaf curl disease on tomato and tobacco in China. It is interesting that TbCSV induced severe upward leaf curling in Nicotiana benthamiana, but in the presence of TbCSB, symptoms changed to be downward leaf curling. However, the mechanism of interactions between viral pathogenicity, host defense, viral-betasatellite interactions and virus-host interactions remains unclear.
methodsIn this study, RNA-seq was used to analyze differentially expressed genes (DEGs) in N. benthamiana plants infected by TbCSV (Y35A) and TbCSV together with TbCSB (Y35AB) respectively.
resultsThrough mapping to N. benthamiana reference genome, 59,814 unigenes were identified. Transcriptome analysis revealed that a total of 4081 and 3196 DEGs were identified in Y35AB vs CK (control check) and Y35A vs CK, respectively. Both GO and KEGG analyses were conducted to classify the DEGs. Ten of the top 15 GO terms were enriched in both DEGs of Y35AB vs CK and Y35A vs CK, and these enriched GO terms mainly classified into three categories including biological process, cellular component and molecular function. KEGG pathway analysis indicated that 118 and 111 pathways were identified in Y35AB vs CK and Y35A vs CK, respectively, of which nine and six pathways were significantly enriched. Three major pathways in Y35AB vs CK involved in metabolic pathways, carbon metabolism and photosynthesis, while those in Y35A vs CK were related to Ribosome, Glyoxylate and dicarboxylate metabolism and DNA replication. We observed that 8 PR genes were significantly up-regulated and 44 LRR-RLK genes were significantly differentially expressed in Y35A treatment or in Y35AB treatment. In addition, 7 and 13 genes were identified to be significantly changed in biosynthesis and signal transduction pathway of brassinosteroid (BR) and jasmonic acid (JA) respectively.
conclusionsThese results presented here would be particularly useful to further elucidate the response of the host plant against virus infection.
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