ReviewBMC cancer2018
The impact of mammography screening programmes on incidence of advanced breast cancer in Europe: a literature review.
Review in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging for breast cancer detection: An update meta-analysis.Thoracic cancer · 2021Pooled it
- Ten-year survival of women with invasive breast cancer by stage, molecular subtype, and grade combined: a population-based study.The oncologist · 2026Article
- Impact of screening on late-stage breast cancer in the Netherlands: a population-based cohort study (2007-2016).Breast (Edinburgh, Scotland) · 2026Article
- Cancer survival in Lower Silesia: insights from a national oncology network pilot in Poland.Frontiers in oncology · 2026Article
- Evaluation of breast cancer screening programmes: Candidate performance indicators and their association with breast cancer mortality.Breast (Edinburgh, Scotland) · 2025Article
- Patients Will Benefit if We Expand Cancer Registries to Capture Method of Detection.Journal of registry management · 2023Article
- Deep-Learning-Driven Full-Waveform Inversion for Ultrasound Breast Imaging.Sensors (Basel, Switzerland) · 2021Article
- Identifying county-level factors for female breast cancer incidence rate through a large-scale population study.Applied geography (Sevenoaks, England) · 2020Article
- Mammography screening reduces rates of advanced and fatal breast cancers: Results in 549,091 women.Cancer · 2020Article
- Long-term Incidence and Mortality Trends for Breast Cancer in Germany.Geburtshilfe und Frauenheilkunde · 2020Article
- Assessment of Breast Cancer Mortality Trends Associated With Mammographic Screening and Adjuvant Therapy From 1986 to 2013 in the State of Victoria, Australia.JAMA network open · 2020Article
- Incidence of advanced-stage breast cancer in regular participants of a mammography screening program: a prospective register-based study.BMC cancer · 2020Article
- Breast cancer in low-middle income countries: abnormality in splicing and lack of targeted treatment options.American journal of cancer research · 2020Review
- Breast cancer mortality trends in Europe among women in perimenopausal and postmenopausal age (45+).Archives of medical science : AMS · 2020Article
- The clinical significance of CHEK1 in breast cancer: a high-throughput data analysis and immunohistochemical study.International journal of clinical and experimental pathology · 2019Article
- Impact of Access to Breast Care For West Texas Program on Early Detection and Regional Breast Cancer Mortality.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObservational studies have reported conflicting results on the impact of mammography service screening programmes on the advanced breast cancer rate (ABCR), a correlation that was firmly established in randomized controlled trials. We reviewed and summarized studies of the effect of service screening programmes in the European Union on ABCR and discussed their limitations.
methodsThe PubMed database was searched for English language studies published between 01-01-2000 and 01-06-2018. After inspection of titles and abstracts, 220 of the 8644 potentially eligible papers were considered relevant. Their abstracts were reviewed by groups of two authors using predefined criteria. Fifty studies were selected for full paper review, and 22 of these were eligible. A theoretical framework for their review was developed. Review was performed using a ten-point checklist of the methodological caveats in the analysis of studies of ABCR and a standardised assessment form designed to extract quantitative and qualitative information.
resultsMost of the evaluable studies support a reduction in ABCR following the introduction of screening. However, all studies were challenged by issues of design and analysis which could at least potentially cause bias, and showed considerable variation in the estimated effect. Problems were observed in duration of follow-up time, availability of reliable reference ABCR, definition of advanced stage, temporal variation in the proportion of unknown-stage cancers, and statistical approach.
conclusionsWe conclude that much of the current controversy on the impact of service screening programmes on ABCR is due to observational data that were gathered and/or analysed with methodological approaches which could not capture stage effects in full. Future research on this important early indicator of screening effectiveness should focus on establishing consensus in the correct methodology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.