ArticleBMC microbiology2018
A decay effect of the growth rate associated with genome reduction in Escherichia coli.
Article in BMC microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Time Series Data Mining for Linking the Shape of Bacterial Growth Curves to Biological Functions.Computational and structural biotechnology journal · 2026Article
- Data-driven analysis reveals distinct genomic and environmental contributions to bacterial growth curves.Scientific reports · 2025Article
- Evaluating the Effect of an Essential Oil Blend on the Growth and Fitness of Gram-Positive and Gram-Negative Bacteria.Biology · 2025Article
- Repurposing fusidic acid as an antimicrobial against enterococci with a low probability of resistance development.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Multiplex gene knockout raises Ala-Gln production by Escherichia coli expressing amino acid ester acyltransferase.Applied microbiology and biotechnology · 2023Article
- Machine learning-assisted medium optimization revealed the discriminated strategies for improved production of the foreign and native metabolites.Computational and structural biotechnology journal · 2023Article
- Investigating the effect of nanoparticle on phenanthrene biodegradation by Labedella gwakjiensis strain KDI.Biodegradation · 2022Article
- A unified and simple medium for growing model methanogens.Frontiers in microbiology · 2022Article
- Contribution of the genomic and nutritional differentiation to the spatial distribution of bacterial colonies.Frontiers in microbiology · 2022Article
- Random genome reduction coupled with polyhydroxybutyrate biosynthesis to facilitate its accumulation inFrontiers in bioengineering and biotechnology · 2022Article
- Chlorhexidine leads to the evolution of antibiotic-resistant Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- The rise and the fall of aMicrobial genomics · 2021Article
- Correlation between the spatial distribution and colony size was common for monogenetic bacteria in laboratory conditions.BMC microbiology · 2021Article
- Targeted Genome Reduction ofFrontiers in bioengineering and biotechnology · 2021Article
- Single Mathematical Parameter for Evaluation of the Microorganisms' Growth as the Objective Function in the Optimization by the DOE Techniques.Microorganisms · 2020Article
- Clustering of Bacterial Growth Dynamics in Response to Growth Media by Dynamic Time Warping.Microorganisms · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBacterial growth is an important topic in microbiology and of crucial importance to better understand living cells. Bacterial growth dynamics are quantitatively examined using various methods to determine the physical, chemical or biological features of growing populations. Due to methodological differences, the exponential growth rate, which is a parameter that is representative of growth dynamics, should be differentiated. Ignoring such differentiation in the growth analysis might overlook somehow slight but significant changes in cellular features of the growing population. Both experimental and theoretical investigations are required to address these issues.
resultsThis study experimentally verified the differentiation in growth rates attributed to different methodologies, and demonstrated that the most popular method, optical turbidity, led to the determination of a lower growth rate in comparison to the methods based on colony formation and cellular adenosine triphosphate, due to a decay effect of reading OD
conclusionsThe present study provides not only an improved theoretical tool for the high-throughput studies on bacterial growth dynamics linking with optical turbidity to biological meaning, but also a novel insight of the genome reduction correlated decay effect, which potentially reflects the changing cellular features during population increase. It is valuable for understanding the genome evolution and the fitness increase in microbial life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.