Evidence map›Paper›PMID 30176291›Full record

ArticleCellular signalling2018

Phosphorylation state of Ser

Ela Markovsky, Elisa de Stanchina, Aryeh Itzkowitz, Adriana Haimovitz-Friedman, Susan A Rotenberg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular signalling, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Tubulin Complexity in Cancer and Metastasis.Advances in experimental medicine and biology · 2024
    Review
  4. Article
  5. Targeting cytoskeletal phosphorylation in cancer.Exploration of targeted anti-tumor therapy · 2021
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ela MarkovskyThe Department of Radiation Oncology, USA.
Elisa de StanchinaAntitumor Assessment Core Facility of Memorial Sloan-Kettering Cancer Institute, USA.
Aryeh ItzkowitzDepartment of Chemistry & Biochemistry, Queens College, USA.
Adriana Haimovitz-FriedmanThe Department of Radiation Oncology, USA.
Susan A RotenbergDepartment of Chemistry & Biochemistry, Queens College, USA; Graduate Center of The City University of New York, USA. Electronic address: Susan.Rotenberg@qc.cuny.edu.
Memorial Sloan Kettering Cancer Center · USQueens College, CUNY · USQueens University of Charlotte · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
MSKCC Pilot Center for Precision Disease ModelingU54OD020355 · OD · SLOAN-KETTERING INST CAN RESEARCH · PI LOWE, SCOTT W., SOLIT, DAVID B. · 2015 to 2019
$9.9M
Protein Kinase C Substrates in Human Breast CancerR15CA125632 · NCI · QUEENS COLLEGE · PI ROTENBERG, SUSAN A. · 2007 to 2013
$930k
NCI NIH HHS P30 CA008748NCI NIH HHS R15 CA125632NIH HHS U54 OD020355
6 · The paper itself

Abstract

Engineered overexpression of protein kinase Cα (PKCα) is known to phosphorylate Ser

Indexed as

Epithelial-Mesenchymal TransitionTubulinAnimalsAntigens, CDBreast NeoplasmsCadherinsCell Line, TumorCell MovementCell ProliferationFemaleHumansLung NeoplasmsMiceMice, NudeMutationNeoplasm MetastasisAntigens, CDCadherinsCDH1 protein, humanCDH2 protein, humanPRKCA protein, humanProtein Kinase C-alphaTubulinBiomarkerCadherin switchCell cycleEMTProtein kinase CSpindle fibers

Identifiers

PMID30176291
PMCPMC6765385
OpenAlexW2889079019

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.