Evidence map›Paper›PMID 30176005›Full record

ArticleJournal of visualized experiments : JoVE2018

Taste Exam: A Brief and Validated Test.

Jennifer E Douglas, Corrine J Mansfield, Charles J Arayata, Beverly J Cowart, Lauren R Colquitt, Ivy W Maina, Mariel T Blasetti, Noam A Cohen, Danielle R Reed

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Subjective versus Psychophysical Measures of Chemosensory Alterations following COVID-19.ORL; journal for oto-rhino-laryngology and its related specialties · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer E DouglasPerelman School of Medicine at the University of Pennsylvania; Monell Chemical Senses Center.
Corrine J MansfieldMonell Chemical Senses Center.
Charles J ArayataMonell Chemical Senses Center.
Beverly J CowartMonell Chemical Senses Center.
Lauren R ColquittMonell Chemical Senses Center.
Ivy W MainaPerelman School of Medicine at the University of Pennsylvania; Monell Chemical Senses Center.
Mariel T BlasettiDepartment of Otorhinolaryngology-Head and Neck Surgery, Division of Rhinology, Hospital of the University of Pennsylvania.
Noam A CohenDepartment of Otorhinolaryngology-Head and Neck Surgery, Division of Rhinology, Hospital of the University of Pennsylvania.
Danielle R ReedMonell Chemical Senses Center; reed@monell.org.

Funding

Chronic Rhinosinusitis and genetics of bitter taste receptorsR01DC013588 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI COHEN, NOAM A · 2014 to 2018
$2.4M
Allele specific expression of TAS2R38 in human taste and nasal tissueR21DC013886 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI COHEN, NOAM A, REED, DANIELLE RENEE · 2015 to 2016
$508k
Targeted genotyping and gene expression with the QuantStudio 12K FlexS10OD018125 · OD · MONELL CHEMICAL SENSES CENTER · PI REED, DANIELLE RENEE · 2015 to 2015
$185k
NIDCD NIH HHS R01 DC013588NIDCD NIH HHS R21 DC013886NIH HHS S10 OD018125
6 · The paper itself

Abstract

The emerging importance of taste in medicine and biomedical research, and new knowledge about its genetic underpinnings, has motivated us to supplement classic taste-testing methods in two ways. First, we explain how to do a brief assessment of the mouth, including the tongue, to ensure that taste papillae are present and to note evidence of relevant disease. Second, we draw on genetics to validate taste test data by comparing reports of perceived bitterness intensity and inborn receptor genotypes. Discordance between objective measures of genotype and subjective reports of taste experience can identify data collection errors, distracted subjects or those who have not understood or followed instructions. Our expectation is that fast and valid taste tests may persuade researchers and clinicians to assess taste regularly, making taste testing as common as testing for hearing and vision. Finally, because many tissues of the body express taste receptors, taste responses may provide a proxy for tissue sensitivity elsewhere in the body and, thereby, serve as a rapid, point-of-care test to guide diagnosis and a research tool to evaluate taste receptor protein function.

Indexed as

AdultFemaleHumansMaleTasteTaste BudsTongueYoung Adult

Identifiers

PMID30176005
PMCPMC6128106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.