ArticleeLife2018
Adaptation after vastus lateralis denervation in rats demonstrates neural regulation of joint stresses and strains.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Brain-body-task co-adaptation can improve autonomous learning and speed of bipedal walking.Bioinspiration & biomimetics · 2024Article
- Kinematics but not kinetics alterations to single-leg drop jump movements following a subject-tailored fatiguing protocol suggest an increased risk of ACL injury.Frontiers in sports and active living · 2024Article
- Whole leg compression garments influence lower limb kinematics and associated muscle synergies during running.Frontiers in bioengineering and biotechnology · 2024Article
- Muscle-driven simulations and experimental data of cycling.Scientific reports · 2023Article
- Neuromechanical Properties of the Vastus Medialis and Vastus Lateralis in Adolescents With Patellofemoral Pain.Orthopaedic journal of sports medicine · 2023Article
- Inhibition of knee joint sensory afferents alters covariation across strides between quadriceps muscles during locomotion.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Neuromuscular control: from a biomechanist's perspective.Frontiers in sports and active living · 2023Review
- Muscle synergies analysis shows altered neural strategies in women with patellofemoral pain during walking.PloS one · 2023Article
- Ultrasonographic assessment of skeletal muscles after experimentally induced neurogenic inflammation (facet injury) in rats.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Estimating muscle activation from EMG using deep learning-based dynamical systems models.Journal of neural engineering · 2022Article
- Evidence for constancy in the modularity of trunk muscle activity preceding reaching: implications for the role of preparatory postural activity.Journal of neurophysiology · 2021Article
- A cross-species neural integration of gravity for motor optimization.Science advances · 2021Article
- The Effects of Mechanical Scale on Neural Control and the Regulation of Joint Stability.International journal of molecular sciences · 2021Review
- Coordination amongst quadriceps muscles suggests neural regulation of internal joint stresses, not simplification of task performance.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Adaptation of muscle activation after patellar loading demonstrates neural control of joint variables.Scientific reports · 2019Article
- Do individual differences in the distribution of activation between synergist muscles reflect individual strategies?Experimental brain research · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
In order to produce movements, muscles must act through joints. The translation from muscle force to limb movement is mediated by internal joint structures that permit movement in some directions but constrain it in others. Although muscle forces acting against constrained directions will not affect limb movements, such forces can cause excess stresses and strains in joint structures, leading to pain or injury. In this study, we hypothesized that the central nervous system (CNS) chooses muscle activations to avoid excessive joint stresses and strains. We evaluated this hypothesis by examining adaptation strategies after selective paralysis of a muscle acting at the rat's knee. We show that the CNS compromises between restoration of task performance and regulation of joint stresses and strains. These results have significant implications to our understanding of the neural control of movements, suggesting that common theories emphasizing task performance are insufficient to explain muscle activations during behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.