Evidence map›Paper›PMID 30175942›Full record

ArticleJournal of biomolecular structure & dynamics2019

Modeling the structural and dynamical changes of the epithelial calcium channel TRPV5 caused by the A563T variation based on the structure of TRPV6.

Lingyun Wang, Ross P Holmes, Ji-Bin Peng

Open access · greenAbstract read
In one paragraph

Article in Journal of biomolecular structure & dynamics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lingyun Wanga Department of Medicine, Division of Nephrology , Nephrology Research and Training Center, University of Alabama at Birmingham , Birmingham , AL , USA.
Ross P Holmesb Department of Urology , University of Alabama at Birmingham , Birmingham , AL , USA.
Ji-Bin Penga Department of Medicine, Division of Nephrology , Nephrology Research and Training Center, University of Alabama at Birmingham , Birmingham , AL , USA.
Pediatric Nephrology of Alabama · USUniversity of Alabama at Birmingham · US

Funding

Hypercalciuria and TRPV6-mediated Active Calcium Reabsorption in the Proximal TubuleR01DK104924 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PENG, JI-BIN · 2017 to 2021
$1.7M
NIDDK NIH HHS R01 DK104924
6 · The paper itself

Abstract

TRPV5, transient receptor potential cation channel vanilloid subfamily member 5, is an epithelial Ca

Indexed as

Molecular Dynamics SimulationPolymorphism, Single NucleotideBinding SitesCalciumCalcium ChannelsHumansModels, MolecularProtein BindingProtein ConformationTRPV Cation ChannelsCalciumCalcium ChannelsTRPV5 protein, humanTRPV6 protein, humanTRPV Cation ChannelsA563T variationcalcium transportCa-selective channelkidney stoneTRPV5

Identifiers

PMID30175942
PMCPMC6397782
OpenAlexW2889690434

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.