Evidence map›Paper›PMID 30175647›Full record

ArticleScandinavian journal of primary health care2018

Predictors of Symptom Duration and Bacteriuria in Uncomplicated Urinary Tract Infection.

Marianne Bollestad, Ingvild Vik, Nils Grude, Morten Lindbæk

Open access · goldAbstract read
In one paragraph

Article in Scandinavian journal of primary health care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marianne Bollestada The Antibiotic Centre of Primary Care, Department of General Practice, Institute of Health and Society , University of Oslo , Oslo , Norway.
Ingvild Vika The Antibiotic Centre of Primary Care, Department of General Practice, Institute of Health and Society , University of Oslo , Oslo , Norway.
Nils Grudea The Antibiotic Centre of Primary Care, Department of General Practice, Institute of Health and Society , University of Oslo , Oslo , Norway.
Morten Lindbæka The Antibiotic Centre of Primary Care, Department of General Practice, Institute of Health and Society , University of Oslo , Oslo , Norway.
University of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify baseline predictors of symptom duration after empirical treatment for uncomplicated urinary tract infection (UTI) and significant bacteriuria in a cohort of women treated for UTI.

designProspective single-centre cohort study.

settingOutpatient clinic in Norway. PATIENTS: From September 2010 to November 2011, 441 women aged 16-55 years with symptoms of uncomplicated UTI were included.

resultsDipstick findings of leukocyte esterase 1 + (incidence rate ratio (IRR) 1.93, 95% confidence interval (CI) 1.23-3.01, p < 0.01) and microbe resistant to mecillinam treatment (IRR 1.41, 95% CI 1.07-1.89, p = 0.02) predicted longer symptom duration. More pronounced symptoms did not predict longer symptom duration (IRR 1.18, 95% CI 0.94-1.46, p = 0.15) or significant bacteriuria (odds ratio [OR] 1.16, 95% CI 0.72-1.88, p = 0.54). Leukocyte esterase 2 + (OR 2.51, 95% CI 0.92-6.83, p = 0.07) or 3 + (OR 2.40, 95% CI 0.88-6.05, p = 0.09) and nitrite positive urine dipstick test (OR 3.22, 95% CI 1.58-7.01, p = <0.01) were associated with bacteriuria.

conclusionMore pronounced symptoms did not correlate with significant bacteriuria or symptom duration after empirical treatment for acute cystitis. One might reconsider the current practice of treating uncomplicated UTI based on symptoms alone. Key Points Treatment strategies for milder infectious diseases must consider ways of reducing antibiotic consumption to decelerate the increase in antibiotic resistance. Our findings suggest that more emphasis should be put on urine dipstick results and bacteriological findings in the clinical setting. One might reconsider the current practice of treating uncomplicated UTIs based on symptoms alone.

Indexed as

Acute DiseaseAdolescentAdultAnti-Bacterial AgentsBacteriuriaCystitisDrug Resistance, MicrobialFemaleHumansLogistic ModelsMiddle AgedNorwayPredictive Value of TestsProspective StudiesRisk FactorsTime FactorsAnti-Bacterial Agentsafter-hours carebacteriuriafemale urogenital diseasesPrimary health careurinary tract infection

Identifiers

PMID30175647
PMCPMC6381539
OpenAlexW2891963011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.