Evidence map›Paper›PMID 30175390›Full record

ArticleEJNMMI physics2018

Comparison of radiobiological parameters for

Yaser H Gholami, Kathy P Willowson, Nicholas J Forwood, Rozelle Harvie, Nicholas Hardcastle, Regina Bromley, HyunJu Ryu, Samuel Yuen, Viive M Howell, Zdenka Kuncic and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Review
  3. Systemic effects ofEuropean journal of nuclear medicine and molecular imaging · 2025
    Article
  4. Review
  5. Quantitative imaging in medicine and surgery · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Understanding the Radiobiological Mechanisms Induced byInternational journal of molecular sciences · 2022
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Evaluation of the PSMA-Binding LigandInternational journal of molecular sciences · 2021
    Article
  17. Quantitative PET in the 2020s: a roadmap.Physics in medicine and biology · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yaser H GholamiUniversity of Sydney, School of Physics, Sydney, Australia.
Kathy P WillowsonUniversity of Sydney, School of Physics, Sydney, Australia.
Nicholas J ForwoodRoyal North Shore Hospital (RNSH), Department of Nuclear Medicine, Sydney, Australia.
Rozelle HarvieBill Walsh Translational Cancer Research Laboratory, The Kolling Institute, Northern Sydney Local Health District, Sydney, Australia.
Nicholas HardcastleRoyal North Shore Hospital (RNSH), Department of Radiation Oncology, Sydney, Australia.
Regina BromleyRoyal North Shore Hospital (RNSH), Department of Radiation Oncology, Sydney, Australia.
HyunJu RyuRoyal North Shore Hospital (RNSH), Department of Nuclear Medicine, Sydney, Australia.
Samuel YuenBill Walsh Translational Cancer Research Laboratory, The Kolling Institute, Northern Sydney Local Health District, Sydney, Australia.
Viive M HowellBill Walsh Translational Cancer Research Laboratory, The Kolling Institute, Northern Sydney Local Health District, Sydney, Australia.
Zdenka KuncicUniversity of Sydney, School of Physics, Sydney, Australia.
Dale L BaileyUniversity of Sydney, School of Physics, Sydney, Australia. dale.bailey@sydney.edu.au.ORCID http://orcid.org/0000-0001-9154-7957
The University of Sydney · AURoyal North Shore Hospital · AUNorthern Sydney Local Health District · AU

Funding

ANSTO/Australian & New Zealand Society of Nuclear Medicine Research Grant 2016
6 · The paper itself

Abstract

backgroundDose rate variation is a critical factor affecting radionuclide therapy (RNT) efficacy. Relatively few studies to date have investigated the dose rate effect in RNT. Therefore, the aim of this study was to benchmark

resultsThree human colorectal carcinoma (CRC) cell lines (HT29, HCT116, SW48) were exposed to

conclusionThese results demonstrate that the efficacy of RNT is dependent on the initial dose rate at which radiation is delivered. Therefore, for a relatively long half-life radionuclide such as

Indexed as

External beam radiotherapy (EBRT)Radionuclide therapy (RNT)Yttrium-90

Identifiers

PMID30175390
PMCPMC6119681
OpenAlexW2807351458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.