Evidence map›Paper›PMID 30175374›Full record

ArticleSingapore medical journal2018

Accuracy and clinical outcomes of coronary CT angiography for patients with suspected coronary artery disease: a single-centre study in Singapore.

Awesh Shamrao Gambre, Charlene Liew, Gayan Hettiarachchi, Sheldon Shao Guang Lee, Michael MacDonald, Carmen Jia Wen Kam, Angeline Choo Choo Poh

Abstract read
In one paragraph

Article in Singapore medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Awesh Shamrao GambreDepartment of Radiology, Changi General Hospital, Singapore.
Charlene LiewDepartment of Radiology, Changi General Hospital, Singapore.
Gayan HettiarachchiDepartment of Radiology, Changi General Hospital, Singapore.
Sheldon Shao Guang LeeDepartment of Cardiology, Changi General Hospital, Singapore.
Michael MacDonaldDepartment of Cardiology, Changi General Hospital, Singapore.
Carmen Jia Wen KamClinical Trials and Research Unit, Changi General Hospital, Singapore.
Angeline Choo Choo PohDepartment of Radiology, Changi General Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aimed to assess the accuracy and outcomes of coronary computed tomography angiography (CCTA) performed in a regional hospital in Singapore.

methodsThe Changi General Hospital CCTA database was retrospectively analysed over a 24-month period. Electronic hospital records, catheter coronary angiography (CCA) and CCTA electronic databases were used to gather data on major adverse cardiovascular events (MACE) and CCA results. CCTA findings were deemed positive if coronary artery stenosis ≥ 50% was reported or if the stenosis was classified as moderate or severe. CCA findings were considered positive if coronary artery stenosis ≥ 50% was reported.

resultsThe database query returned 679 patients who had undergone CCTA for the evaluation of suspected coronary artery disease. Of the 101 patients in the per-patient accuracy analysis group, there were six true negatives, one false negative, 81 true positives and 13 false positives, resulting in a negative predictive value of 85.7% and positive predictive value of 86.2%. The mean age of the study sample was 53 ± 13 years and 255 (37.6%) patients were female. Mean duration of patient follow-up was 360 days. Of the 513 negative CCTA patients, none developed MACE during the follow-up period, and of the 164 positive CCTA patients, 19 (11.6%) developed MACE (p < 0.001).

conclusionAnalysis of CCTA studies suggested accuracy and outcomes that were consistent with published clinical data. There was a one-year MACE-free warranty period following negative CCTA findings.

Indexed as

Computed Tomography AngiographyCoronary AngiographyAdolescentAdultAgedAged, 80 and overCoronary Artery DiseaseCoronary StenosisDatabases, FactualElectronic Health RecordsFemaleHumansMaleMiddle AgedPrognosisReproducibility of Resultscoronary angiographycoronary artery diseasecoronary stenosisCT angiographyprognosis

Identifiers

PMID30175374
PMCPMC6109833

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