Evidence map›Paper›PMID 30175261›Full record

ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2018

Leucine modulates the IPEC-J2 cell proteome associated with cell proliferation, metabolism and phagocytosis.

Xiangbing Mao, Man Ren, Daiwen Chen, Bing Yu, Lianqiang Che, Jun He, Junqiu Luo, Yuheng Luo, Jianping Wang, Hui Sun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Xiangbing MaoAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Man RenAnimal Science Collage, Anhui Science and Technology University, Chuzhou 233100, China.
Daiwen ChenAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Bing YuAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Lianqiang CheAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Jun HeAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Junqiu LuoAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Yuheng LuoAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Jianping WangAnimal Nutrition Institute, Sichuan Agricultural University, Ya'an 625014, China.
Hui SunCollege of Animal Science and Technology, Jilin Agricultural University, Changchun 130033, China.
Sichuan Agricultural University · CNAnhui Science and Technology University · CNJilin Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leucine can affect intestinal protein expressions, and improve mucosal immune function. However, little study has been conducted to determine the change of protein component by leucine treatment in intestine epithelial cells. The present study was to cover the key proteins and cell pathways that could be regulated by leucine treatment in porcine intestinal epithelial cell line (IPEC-J2) cells with the approach of proteome analysis. A total number of 3,211 proteins were identified in our approach by searching the database of Uniprot

Indexed as

Apoptosis and metabolismCell proliferationIPEC-J2 cellsLeucinePhagocytosisProteome

Identifiers

PMID30175261
PMCPMC6116325
OpenAlexW2795947151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.