ArticleAnimal nutrition (Zhongguo xu mu shou yi xue hui)2018
Potential antioxidant bioactive peptides from camel milk proteins.
Article in Animal nutrition (Zhongguo xu mu shou yi xue hui), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Food Protein-Derived Antioxidant Peptides: Molecular Mechanism, Stability and Bioavailability.Biomolecules · 2022Pooled it
- Effect of Camel Milk on Glucose Homeostasis in Patients with Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Nutrients · 2022Pooled it
- NRF2/SLC7A11/GPX4 Antioxidant Axis Suppression by Camel Milk Whey Protein Sensitizes MCF-7 Breast Cancer Cells to Cisplatin.International journal of molecular sciences · 2026Article
- Camel Milk and Its Bioactive Components in Diseases Associated with Aging: A Narrative Review.Nutrients · 2026Review
- The Desert Duo: A Narrative Review on How Camel Milk and Date Fruits Combat Oxidative Stress and Enhance Metabolic Health.Antioxidants (Basel, Switzerland) · 2026Review
- Accurate structure-activity relationship prediction of antioxidant peptides using a multimodal deep learning framework.Journal of cheminformatics · 2025Article
- Effects of Transglutaminase and Heat Treatment on the Structure and Gelation Properties of Camel Casein Protein.Foods (Basel, Switzerland) · 2025Article
- Carbonate alkalinity induces stress responses and renal and metabolic disorders in Nile tilapia: mitigation by camel whey protein hydrolysate diet.Fish physiology and biochemistry · 2025Article
- Camel milk: Nutritional composition, therapeutic properties, and benefits for human health.Open veterinary journal · 2024Review
- Stability of Fly Maggot Peptides and Its Alleviating Effect on Lipopolysaccharide Combined with Hemocoagulase Oxidative Stress in Arbor Acres Chicks.Veterinary sciences · 2024Article
- Functional Peptides from Yak Milk Casein: Biological Activities and Structural Characteristics.International journal of molecular sciences · 2024Review
- Identification of natural antimicrobial peptides mimetic to inhibit CaJournal of bioenergetics and biomembranes · 2024Article
- Study of the Milkability of the Mediterranean Italian Buffalo and the Tunisian Maghrebi Camel According to Parity and Lactation Stage.Animals : an open access journal from MDPI · 2024Article
- Antioxidant Activity of Sweet Whey Derived from Bovine, Ovine and Caprine Milk Obtained from Various Small-Scale Cheese Plants in Greece before and after In Vitro Simulated Gastrointestinal Digestion.Antioxidants (Basel, Switzerland) · 2023Article
- Comparative Study of Camel Milk from Different Areas of Xinjiang Province in China.Food science of animal resources · 2023Article
- Shifting archetype to nature's hidden gems: from sources, purification to uncover the nutritional potential of bioactive peptides.3 Biotech · 2023Review
- Camel milk ameliorates diabetes in pigs by preventing oxidative stress, inflammation and enhancing beta cell function.Journal of diabetes and metabolic disorders · 2022Article
- Ameliorative Effects of Camel Milk and Its Exosomes on Diabetic Nephropathy in Rats.Membranes · 2022Article
- Nutritional values and health benefits of dromedary camel meat.Animal frontiers : the review magazine of animal agriculture · 2022Article
- Prospective Role of Bioactive Molecules and Exosomes in the Therapeutic Potential of Camel Milk against Human Diseases: An Updated Perspective.Life (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Camel milk is traditionally considered to have medicinal characteristics that it has potential health benefits and could help to treat several illnesses. Particularly, it is closest to human breast milk and has high levels of nutrients and bioactive components. The aim of this study was to explore the antioxidant peptides derived from protein fractions of camel milk. Camel milk proteins (CMP) were fractionated into camel casein protein (CCP) and camel whey protein (CWP), which were hydrolyzed with pepsin to produce peptic digests P-CCP and P-CWP, respectively. RP-HPLC was used for fractionation of the peptides from the P-CCP and P-CWP. The antioxidant activities were evaluated using superoxide anion generating system of xanthine oxidase (XOD) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay. Active peptides were analyzed using matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF-MS) whereas a number of antioxidant peptides, with masses ranging from 913 to 2,951 Da, derived mainly from alpha-casein, lactophorin and lactoferrin, were identified. When yeast cells are used as a system for modeling mitochondrial disease, the peptides in caseins and whey fractions significantly enhanced the tolerance of yeast cells against peroxide-induced oxidative stress. The results show that both caseins and whey proteins of camel milk possess bioactive peptides with significant radical-scavenging activities and thus herald a fascinating opportunity for their potential as nutraceuticals or therapeutic peptides for prevention and treatment of oxidative stress-associated diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.