Evidence map›Paper›PMID 30175152›Full record

ArticleBioMed research international2018

Ghrelin Ameliorates Angiotensin II-Induced Myocardial Fibrosis by Upregulating Peroxisome Proliferator-Activated Receptor Gamma in Young Male Rats.

Qian Wang, Xin Sui, Rui Chen, Pei-Yong Ma, Yong-Liang Teng, Tao Ding, Dian-Jun Sui, Ping Yang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Gut Molecules in Cardiometabolic Diseases: The Mechanisms behind the Story.International journal of molecular sciences · 2023
    Review
  3. "Sibling" battle or harmony: crosstalk between nesfatin-1 and ghrelin.Cellular and molecular life sciences : CMLS · 2022
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Qian WangDepartment of Cardiology, China-Japan Union Hospital, Jilin University, Changchun 130033, China.
Xin SuiCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130021, China.
Rui ChenCollege of Pharmacy, Changchun University of Chinese Medicine, Changchun 130021, China.
Pei-Yong MaDepartment of Cardiology, China-Japan Union Hospital, Jilin University, Changchun 130033, China.
Yong-Liang TengThe First Hospital of Jilin University, Changchun 130021, China.
Tao DingTraditional Medicine Institute of Jilin Province, Changchun 130021, China.
Dian-Jun SuiDepartment of Cardiology, China-Japan Union Hospital, Jilin University, Changchun 130033, China.ORCID 0000-0002-5875-4679
Ping YangDepartment of Cardiology, China-Japan Union Hospital, Jilin University, Changchun 130033, China.ORCID 0000-0003-0114-4973
Union Hospital · CNChangchun University of Chinese Medicine · CNJilin Academy of Traditional Chinese Medicine · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensin (Ang) II contributes to the formation and development of myocardial fibrosis. Ghrelin, a gut peptide, has demonstrated beneficial effects against cardiovascular disease. In the present study, we explored the effect and related mechanism of Ghrelin on myocardial fibrosis in Ang II-infused rats. Adult Sprague-Dawley (SD) rats were divided into 6 groups: Control, Ang II (200ng/kg/min, microinfusion), Ang II+Ghrelin (100

Indexed as

Angiotensin IIAnimalsCells, CulturedFibroblastsFibrosisGhrelinMaleMyocardiumPPAR gammaRatsRats, Sprague-DawleyTransforming Growth Factor beta1Angiotensin IIGhrelinPPAR gammaPPAR gamma, ratTransforming Growth Factor beta1

Identifiers

PMID30175152
PMCPMC6098901
OpenAlexW2886851946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.