Evidence map›Paper›PMID 30175147›Full record

Trial reportBioMed research international2018

Contrast-Enhanced Ultrasound in Residual Tumor of Hepatocellular Carcinoma following Transarterial Chemoembolization: Is It Helpful for Tumor Response?

Tian'an Jiang, Qiyu Zhao, Min Huang, Junhui Sun, Guo Tian

Open access · hybridAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tian'an JiangDepartment of Ultrasound, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, China.ORCID 0000-0002-7672-8394
Qiyu ZhaoDepartment of Ultrasound, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, China.
Min HuangDepartment of Ultrasound, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, China.
Junhui SunHepatobiliary & Pancreatic Intervention Center, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, China.ORCID 0000-0003-1947-8330
Guo TianDepartment of Ultrasound, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, China.
Zhejiang University · CNBlood Center of Zhejiang Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the enhancement pattern of residual tumor on contrast-enhanced ultrasonography (CEUS) in patients with hepatocellular carcinoma (HCC) treated with transarterial chemoembolization (TACE).

methodsOur study initially included 76 patients with HCC, 73 of which were finally allocated into two groups: group 1 (43 patients, post-TACE group) and group 2 (30 patients, untreated HCC group). All patients were performed with CEUS using SonoVue, and qualitative and quantitative enhancement characteristics (rise time, peak time, and washout time) were evaluated for the residual tumors. T test or

resultsIn group 1, the mean rise time, peak time, and washout times in group 1 were 16.1±2.7 sec, 31.3±3.1 sec, and 191.0±31.3 sec, respectively. In group 2, these were 15.1±3.5 sec, 30.9±3.2 sec, and 142.6±16.1 sec, respectively. The differences in rise time and peak time were not statistically significant (

conclusionIt suggested that the washout time of post-TACE residual lesions was prolonged compared with untreated HCC nodules on CEUS imaging. Combined with the triple-phase enhancement pattern seen on CEUS, the washout time may provide additional information to guide further treatment for residual tumors.

Indexed as

Chemoembolization, TherapeuticTomography, X-Ray ComputedAdultAgedAged, 80 and overCarcinoma, HepatocellularContrast MediaFemaleHumansLiver NeoplasmsMaleMiddle AgedNeoplasm, ResidualRetrospective StudiesUltrasonographyYoung AdultContrast Media

Identifiers

PMID30175147
PMCPMC6098931
OpenAlexW2886835168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.