Evidence map›Paper›PMID 30175106›Full record

ArticleMicrobial cell (Graz, Austria)2018

Snf1 cooperates with the CWI MAPK pathway to mediate the degradation of Med13 following oxidative stress.

Stephen D Willis, David C Stieg, Kai Li Ong, Ravina Shah, Alexandra K Strich, Julianne H Grose, Katrina F Cooper

Open access · goldAbstract read
In one paragraph

Article in Microbial cell (Graz, Austria), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Potential roles of mediator Complex Subunit 13 in Cardiac Diseases.International journal of biological sciences · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephen D WillisDepartment of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University, Stratford, NJ, 08084, USA.
David C StiegDepartment of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University, Stratford, NJ, 08084, USA.
Kai Li OngDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Ravina ShahDepartment of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University, Stratford, NJ, 08084, USA.
Alexandra K StrichDepartment of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University, Stratford, NJ, 08084, USA.
Julianne H GroseDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Katrina F CooperDepartment of Molecular Biology, Graduate School of Biomedical Sciences, Rowan University, Stratford, NJ, 08084, USA.
Rowan University · USBrigham Young University · US

Funding

Regulation and Function of PAS Kinase - PASsing glucose to control respiration, lipogenesis and cell cycleR15GM100376 · NIGMS · BRIGHAM YOUNG UNIVERSITY · PI GROSE, JULIANNE H. · 2012 to 2022
$1.3M
Stress induced signaling and cyclin C regulation in yeastR15GM113196 · NIGMS · ROWAN UNIVERSITY SCHOOL/OSTEOPATHIC MED · PI COOPER, KATRINA FRANCES · 2015 to 2015
$396k
NIGMS NIH HHS R15 GM100376NIGMS NIH HHS R15 GM113196
6 · The paper itself

Abstract

Eukaryotic cells, when faced with unfavorable environmental conditions, mount either pro-survival or pro-death programs. The conserved cyclin C-Cdk8 kinase plays a key role in this decision. Both are members of the Cdk8 kinase module that, along with Med12 and Med13, associate with the core Mediator complex of RNA polymerase II. In

Indexed as

AMPKCdk8cyclin CH2O2 stressMAPKMed13SCFGrr1signal transductionSnf1ubiquitin mediated destruction

Identifiers

PMID30175106
PMCPMC6116281
OpenAlexW2887899581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.