Evidence map›Paper›PMID 30175048›Full record

ArticleToxicology reports2018

Morphological alterations induced by the exposure to TiO

Xavier Valentini, Pauline Deneufbourg, Paula Paci, Pascaline Rugira, Sophie Laurent, Annica Frau, Dimitri Stanicki, Laurence Ris, Denis Nonclercq

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Role of metal nanomaterials in wound healing - a review.Frontiers in bioengineering and biotechnology · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. General review of titanium toxicity.International journal of implant dentistry · 2019
    Review
  18. Hepatic and Renal Toxicity Induced by TiOJournal of toxicology · 2019
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xavier ValentiniLaboratory of Histology, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Pauline DeneufbourgLaboratory of Neurosciences, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Paula PaciLaboratory of Neurosciences, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Pascaline RugiraLaboratory of Histology, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Sophie LaurentLaboratory of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Institute for Health Sciences and Technology, Institute of Biosciences, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Annica FrauLaboratory of Histology, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Dimitri StanickiLaboratory of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory, University of Mons, Institute for Health Sciences and Technology, Institute of Biosciences, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Laurence RisLaboratory of Neurosciences, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
Denis NonclercqLaboratory of Histology, University of Mons, Institute for Health Sciences and Technology, Faculty of Medicine and Pharmacy, 23, Place du Parc, B-7000 Mons, Belgium.
University of Mons · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nowadays, nanoparticles (NPs) of titanium dioxide (TiO

Indexed as

4-HNE, 4-hydroxynonenalATP, adenosine triphosphateBBB, blood-brain barrierBrainBrdU, 5-Bromo-2′-deoxyuridineCell cultureCNS, central nervous systemDLS, dynamic light scatteringFBS, fetal bovine serumGFAP, glial fibrillary acidic proteinHBSS, Hank's balanced salt solutionIL-10, interleukin-10IL-1β, interleukin-1βIP, intraperitonealMAP2, microtubule-associated protein 2MDA, malondialdehydeNanoparticlesNMDA, N-methyl-D-aspartateNO, nitric oxideNOS, nitric oxide synthaseNPs, nanoparticlesOxidative stressProliferationROS, reactive oxygen speciesSEM, standard error of the meanTNF-α, tumor necrosis factor-α

Identifiers

PMID30175048
PMCPMC6118103
OpenAlexW2888713482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.