Evidence map›Paper›PMID 30174956›Full record

ArticleJournal of pregnancy2018

Prevalence, Infectivity, and Associated Risk Factors of Hepatitis B Virus among Pregnant Women in Yirgalem Hospital, Ethiopia: Implication of Screening to Control Mother-to-Child Transmission.

Anteneh Amsalu, Getachew Ferede, Setegn Eshetie, Agete Tadewos, Demissie Assegu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pregnancy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  8. Seroepidemiology ofBioMed research international · 2018
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  19. Prevalence ofFrontiers in global women's health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anteneh AmsaluDepartment of Medical Microbiology, University of Gondar, Gondar, Ethiopia.ORCID 0000-0001-7919-4546
Getachew FeredeDepartment of Medical Microbiology, University of Gondar, Gondar, Ethiopia.ORCID 0000-0001-9748-7326
Setegn EshetieDepartment of Medical Microbiology, University of Gondar, Gondar, Ethiopia.ORCID 0000-0001-9130-0882
Agete TadewosDepartment of Medical Laboratory Sciences, Hawassa University, Hawassa, Ethiopia.
Demissie AsseguDepartment of Medical Laboratory Sciences, Hawassa University, Hawassa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) positive mother has up to 90% likelihood of mother-to-child transmission (MTCT) of hepatitis B virus (HBV) to newborns in the absence of any prophylaxis or antiviral therapy utilization. However, routine antenatal screening and intervention strategies are not yet practiced in Ethiopia. Therefore, this study was conducted to determine the prevalence, infectivity, and associated risk factors of HBV among pregnant women.

methodsA cross-sectional study was conducted from October 2015 to August 2016 in Yirgalem Hospital. A total of 475 pregnant women were recruited, and data on sociodemography and potential risk factors were collected using a structured questionnaire. In addition, blood samples were tested for HBsAg, and HBsAg positive samples were retested for HBeAg using commercially available strip test. The status of HIV was collected from the records.

resultsThe seroprevalence of HBsAg was 34 (7.2%), of whom 13 (38.8%) were positive for HBeAg. The prevalence of HIV infection was 10.1% (48/475). Ten out of 34 HBV positive cases (29.4%) were coinfected with HIV. The overall HBV/HIV coinfection rate was 2.1% (10/475). Women with history of multiple sexual partners and being HIV positive were significantly associated with HBsAg positivity. Among the study participants, 35.4% were aware of MTCT of HBV and only 12 (2.5%) have taken HBV vaccine.

conclusionsHigh prevalence of HBsAg and HBeAg as well as low awareness and practices of HBV prevention methods suggests that perinatal transmission of HBV might be the prevailing mode of HBV transmission in the study area. Thus, screening of all pregnant women, particularly those who had history of multiple sexual partners and HIV coinfection, and provision of health education about HBV prevention methods are inevitable.

Indexed as

Infectious Disease Transmission, VerticalAdultCoinfectionCross-Sectional StudiesEthiopiaFemaleHealth Knowledge, Attitudes, PracticeHepatitis BHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHIV InfectionsHumansMass ScreeningPregnancyPregnancy Complications, InfectiousHepatitis B e AntigensHepatitis B Surface Antigens

Identifiers

PMID30174956
PMCPMC6098924

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.