ReviewJournal of thoracic disease2018
Bilateral versus single lung transplantation: are two lungs better than one?
Review in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Prognostic validation of the 2019 International Society for Heart and Lung Transplantation chronic lung allograft dysfunction states in lung transplant recipients.ERJ open research · 2026Article
- Successful Single Lung Transplantation in Severe Group III Pulmonary Hypertension.Annals of thoracic surgery short reports · 2026Article
- Revised Deep Learning Semiparametric Regression for Testing and Estimating Treatment Effect Heterogeneity in Observational Studies: A Lung Transplant Case Study.bioRxiv : the preprint server for biology · 2026Article
- Article
- Identical versus compatible blood typing: investigating best practices in lung transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Association Between Early Posttransplant Graft Perfusion and CLAD-Free Survival After Single Lung Transplantation.Journal of transplantation · 2026Article
- Development and Validation of a Hybrid Machine Learning Model to Predict Lung Transplant Outcomes.JAMA network open · 2025Article
- Optimizing patient outcomes in interstitial lung disease through pre- and post-transplant management strategies.World journal of transplantation · 2025Review
- Article
- Donor-derived cell-free DNA is a valuable monitoring tool after single lung transplantation: Multicenter analysis.JHLT open · 2024Article
- Survival Tree Provides Individualized Estimates of Survival After Lung Transplant.The Journal of surgical research · 2024Article
- Pulmonary Embolism Following Lung Transplantation: Prevention and Management.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Review
- Two single lung transplantations from one donor: lung twinning in the LAS era.Respiratory research · 2024Article
- Single Lung Transplant for Secondary Pulmonary Hypertension: The Right Option for the Right Patient.Journal of clinical medicine · 2023Review
- Lung Transplantation Outcomes in Recipients Aged 70 Years or Older and the Impact of Center Volume.Journal of clinical medicine · 2023Article
- Do older surgeons have safer hands? A retrospective cohort study.Journal of cardiothoracic surgery · 2022Article
- Comparing outcomes in patients with end-stage chronic obstructive pulmonary disease: single versus bilateral lung transplants.Interactive cardiovascular and thoracic surgery · 2021Article
- Article
- The influence of the native lung on early outcomes and survival after single lung transplantation.PloS one · 2021Observational
- Targeting Aging Pathways in Chronic Obstructive Pulmonary Disease.International journal of molecular sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
There is a long-standing debate over whether single or bilateral lung transplant provides better short and long-term clinical outcomes. We performed a detailed PubMed search on relevant clinical research publications on single (SLT) and bilateral lung transplantation (BLT). We included studies that were published before and after the implementation of the lung allocation score (LAS). We reviewed disease-specific short- and long-term outcomes associated with each transplantation technique. The majority of published studies are retrospective cohort studies that use institutional data or large patient registries. Outcomes associated with transplantation technique vary by disease specific indication, age, and patient severity. Over the past decade, the relative proportion of bilateral lung transplantation has increased. Increasing adoption of bilateral lung transplant likely reflects the general acceptance of several advantages associated with the technique. However, making a clear, evidence-based decision is difficult in light of the fact that there has never been and probably never will be a randomized trial. Our institutional preference is bilateral lung transplant. However, consideration for the technique should still be made on a case-by-case basis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.