Evidence map›Paper›PMID 30174760›Full record

ArticleThe EPMA journal2018

A new non-invasive diagnostic tool in coronary artery disease: artificial intelligence as an essential element of predictive, preventive, and personalized medicine.

Michael J Zellweger, Andrew Tsirkin, Vasily Vasilchenko, Michael Failer, Alexander Dressel, Marcus E Kleber, Peter Ruff, Winfried März

Open access · bronzeAbstract read
In one paragraph

Article in The EPMA journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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  19. Digital Health Consumers on the Road to the Future.Journal of medical Internet research · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Michael J Zellweger1Cardiology Department, University Hospital, University of Basel, Petersgraben 4, 4031 Basel, Switzerland.ORCID 0000-0001-7027-5622
Andrew TsirkinSoftware and Modeling, Exploris AG, Modeling, Exploris AG, Zürich, Switzerland.
Vasily VasilchenkoSoftware and Modeling, Exploris AG, Modeling, Exploris AG, Zürich, Switzerland.
Michael FailerExploris AG, Zürich, Switzerland.
Alexander DresselDACH Gesellschaft Prävention von Herz-Kreislauf-Erkrankungen e.V., Hamburg, Germany.
Marcus E Kleber5Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Peter RuffExploris AG, Zürich, Switzerland.
Winfried März5Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Exploristics (United Kingdom) · GBD•A•CH-Gesellschaft · DEHeidelberg University · DEMedical University of Graz · ATUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnown coronary artery disease (CAD) risk scores (e.g., Framingham) estimate the CAD-related event risk rather than presence/absence of CAD. Artificial intelligence (AI) is rarely used in this context.

aimsThis study aims to evaluate the diagnostic power of AI (memetic pattern-based algorithm (MPA)) in CAD and to expand its applicability to a broader patient population. METHODS AND

resultsNine hundred eighty-seven patients of the Ludwigshafen Risk and Cardiovascular Health Study (LURIC) were divided into a training (

conclusionsThe successful use of the MPA approach has been demonstrated in a broad-risk spectrum of patients undergoing CAD evaluation, as an element of predictive, preventive, personalized medicine, and may be used instead of further non-invasive diagnostic procedures.

Indexed as

Artificial intelligence-based prediction and decision-makingCoronary artery diseaseDiagnosisMemetic pattern-based algorithmNon-invasive evaluationPPPMRisk scores

Identifiers

PMID30174760
PMCPMC6107459
OpenAlexW2887666513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.