Evidence map›Paper›PMID 30174560›Full record

ArticleContrast media & molecular imaging2018

Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging.

Adam W Autry, Rintaro Hashizume, C David James, Peder E Z Larson, Daniel B Vigneron, Ilwoo Park

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Pilot Study of HyperpolarizedAJNR. American journal of neuroradiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Adam W AutryDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Rintaro HashizumeDepartment of Neurological Surgery and Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.
C David JamesDepartment of Neurological Surgery and Biochemistry and Molecular Genetics, Northwestern University, Chicago, IL, USA.
Peder E Z LarsonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.
Ilwoo ParkDepartment of Radiology, Chonnam National University Medical School, Gwangju, Republic of Korea.ORCID 0000-0001-6022-8363
University of California, San Francisco · USNorthwestern University · USChonnam National University Hospital · KR

Funding

TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI John Kurhanewicz · 2011 to 2026
$19.9M
Training Program in Translational Brain Tumor ResearchT32CA151022 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joseph F Costello · 2010 to 2026
$6.6M
New Instrumentation and Techniques for Hyperpolarized Metabolic and Perfusion MRIR01EB013427 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KURHANEWICZ, JOHN, VIGNERON, DANIEL B · 2013 to 2016
$2.8M
Targeting histone demethylase activity for the treatment of pediatric brainstem gliomaR01NS093079 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HASHIZUME, RINTARO · 2015 to 2019
$1.5M
NCI NIH HHS T32 CA151022NIBIB NIH HHS P41 EB013598NIBIB NIH HHS R01 EB013427NINDS NIH HHS R01 NS093079
6 · The paper itself

Abstract

Objective: The purpose of this study was to demonstrate the feasibility of using hyperpolarized carbon-13 ( Materials and Methods: 3D Results: Anatomical images from DIPG-bearing rats characteristically exhibited T Conclusions: Results from this study characterized pyruvate and lactate metabolism in orthotopic DIPG xenografts and suggest that hyperpolarized

Indexed as

Magnetic Resonance ImagingAnimalsBrain Stem NeoplasmsCarbon IsotopesChildGliomaHumansMaleMetabolomeRatsCarbon-13Carbon Isotopes

Identifiers

PMID30174560
PMCPMC6098895
OpenAlexW2887879106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.