Evidence map›Paper›PMID 30174470›Full record

ReviewKorean journal of radiology

Prostate-Specific Membrane Antigen PET Imaging in Prostate Cancer: Opportunities and Challenges.

So Won Oh, Gi Jeong Cheon

Registry-linked trialAbstract readReview
In one paragraph

Review in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05622162 (Phase III Multicentre Prospective Comparative Study of Detection Rate of 18F-JK-PSMA-7 and of 18F-fluorocholine in Patients With Biochemical Recurrence of Prostate Cancer After Previous Treatment With Curative Intent), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05622162 phase3unknown statusnot on this map

Phase III Multicentre Prospective Comparative Study of Detection Rate of 18F-JK-PSMA-7 and of 18F-fluorocholine in Patients With Biochemical Recurrence of Prostate Cancer After Previous Treatment With Curative Intent

TypeinterventionalSponsorITEL Telecomunicazioni SrlRan2022 to 2024Enrolled106ConditionsProstate Cancer, 18F- Fluorocholine, PSMA PET, RadiotherapyArmsRadiopharmaceutical 18F-JK-PSMA-7, Radiopharmaceutical 18F-Fluorocholine
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A microdose clinical trial to evaluate [European journal of nuclear medicine and molecular imaging · 2021
    Trial
  3. Article
  4. Head-to-HeadDiagnostics (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Cancer imaging : the official publication of the International Cancer Imaging Society · 2023
    Article
  12. Comparison of the Effects of DOTA and NOTA Chelators onDiagnostics (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Recurrent Prostate Cancer Diagnostics withDiagnostics (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

So Won OhDepartment of Nuclear Medicine, Seoul National University Boramae Medical Center, Seoul 07061, Korea.
Gi Jeong CheonDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this systematic review was to describe the characteristics of prostate-specific membrane antigen (PSMA)-targeting PET and their clinical applications in prostate cancer patients. There have been major strides in the design, synthesis of PSMA-targeting PET tracers over the past several years. PSMA-targeting PET tracers can be categorized, according to positron emitters and targeting strategies for the PSMA. The majority of PSMA PET studies has been focused on patients with biochemical recurrence, but additional values of PSMA PET have also been investigated for use in primary staging, treatment planning, response evaluation, and PSMA radioligand therapy. PSMA PET is expected to bring improvements in the management of patients, but the impact of improved diagnosis by PSMA on overall survival remains unanswered. Many challenges still await PSMA PET to expedite the use in the clinical practice. At this early stage, prospective multicenter trials are needed to validate the effectiveness and usefulness of PSMA PET.

Indexed as

Antibodies, MonoclonalCholineContrast MediaHumansMagnetic Resonance ImagingMaleNeoplasm Recurrence, LocalPositron-Emission TomographyProstate-Specific AntigenProstatic NeoplasmsAntibodies, MonoclonalCholineContrast MediaProstate-Specific AntigenPET/MRIProstate cancerProstate-specific membrane antigenProstate-specific PET tracersRecurrence

Identifiers

PMID30174470
PMCPMC6082771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.