ArticlePatient preference and adherence2018
The impact of disease activity and psychological status on quality of life for Chinese patients with primary Sjögren's syndrome.
Article in Patient preference and adherence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Effects of physical activity on health-related outcomes in Sjögren's syndrome: a systematic review and meta-analysis of randomized controlled trials.Frontiers in immunology · 2026Pooled it
- Agomelatine for Sjögren's syndrome: a study on its therapeutic effects and mechanisms.Inflammopharmacology · 2026Article
- A cross-sectional study on dysphagia-related quality of life and its associated factors in chinese patients with sjögren's syndrome.Scientific reports · 2026Article
- Cross-cultural adaptation and validation of the Chinese version of the PSS-QoL questionnaire.PloS one · 2024Observational
- The Translation, Validation and Cultural Adaptation of Questionnaires Assessing the Quality of Life and Fatigue among Patients with Sjogren's Syndrome for the Romanian Context.Clinics and practice · 2023Article
- The interplay between cognition, depression, anxiety, and sleep in primary Sjogren's syndrome patients.Scientific reports · 2022Article
- Exposure-lag-response associations between extreme environmental conditions and primary Sjögren's syndrome.Clinical rheumatology · 2022Article
- Exposure to ambient gaseous pollutant and daily hospitalizations for Sjögren's syndrome in Hefei: A time-series study.Frontiers in immunology · 2022Article
- An Update on the Lived Experience of Dry Mouth in Sjögren's Syndrome Patients.Frontiers in oral health · 2021Review
- Understanding Fatigue in Sjögren's Syndrome: Outcome Measures, Biomarkers and Possible Interventions.Frontiers in immunology · 2021Review
- Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study.Scientific reports · 2020Article
- B7-H3 participates in human salivary gland epithelial cells apoptosis through NF-κB pathway in primary Sjögren's syndrome.Journal of translational medicine · 2019Article
- Dry eye disease also might influence psychological status and quality of life in patients with primary Sjögren's syndrome.Patient preference and adherence · 2018Article
Corrections and comments
- Commented on by
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe primary purpose of the present study was to survey the quality of life (QoL) in primary Sjögren's syndrome (pSS) and to analyze the relationships between disease activity, anxiety/depression, fatigue, pain, age, oral disorders, impaired swallowing, sicca symptoms, and QoL. PATIENTS AND
methodsA survey was conducted on 185 pSS patients and 168 healthy individuals using the Short Form 36 health survey for QoL. Disease activity was assessed using the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index. We examined these data using independent samples
resultsThe result for each domain in Short Form 36 health survey was lower in pSS patients than in healthy controls, especially the score in the dimension of role physical function. In the bivariate analysis, age, pain, fatigue, disease activity, disease complication, anxiety/depression, oral disorders, and impaired swallowing correlated with QoL. Also, in the linear regression model, pain, fatigue, disease activity, impaired swallowing, and anxiety/depression remained the main predictors of QoL.
conclusionpSS patients had a considerably impaired QoL compared to the controls, and pSS could negatively affect the QoL of patients. Measuring QoL should be considered as a vital part of the comprehensive evaluation of the health status of pSS patients, which could contribute some valuable clues in improving the management of disease and treatment decisions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.