Evidence map›Paper›PMID 30174388›Full record

ReviewAnnals of gastroenterology

Newly recognized extratumoral features of colorectal cancer challenge the current tumor-node-metastasis staging system.

Elias Athanasakis, Sofia Xenaki, Maria Venianaki, George Chalkiadakis, Emmanuel Chrysos

Open access · diamondAbstract readReview
In one paragraph

Review in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Challenges with colorectal cancer staging: results of an international study.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elias AthanasakisDepartment of General Surgery, University Hospital of Heraklion Crete, Greece.
Sofia XenakiDepartment of General Surgery, University Hospital of Heraklion Crete, Greece.
Maria VenianakiDepartment of General Surgery, University Hospital of Heraklion Crete, Greece.
George ChalkiadakisDepartment of General Surgery, University Hospital of Heraklion Crete, Greece.
Emmanuel ChrysosDepartment of General Surgery, University Hospital of Heraklion Crete, Greece.
University Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common malignant tumors in humans, colorectal cancer has been extensively studied during the past few decades. Staging colorectal cancer allows clinicians to obtain precise prognostic information and apply specific treatment procedures. Apart from remote metastases, the depth of tumor infiltration and lymph node involvement have traditionally been recognized as the most important factors predicting outcome. Variations in the molecular signature of colorectal cancer have also revealed differences in phenotypic aggressiveness and therapeutic response rates. This article presents a review of the extratumoral environment in colorectal surgery.

Indexed as

Colorectal cancerinvasionTNM stagingtumor buddingtumor deposits

Identifiers

PMID30174388
PMCPMC6102465
OpenAlexW2808488143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.