Evidence map›Paper›PMID 30174378›Full record

ReviewJournal of orthopaedics2018

Risk of falls in patients with knee osteoarthritis undergoing total knee arthroplasty: A systematic review and best evidence synthesis.

Giorgio di Laura Frattura, Giuseppe Filardo, Dario Giunchi, Augusto Fusco, Stefano Zaffagnini, Christian Candrian

Erratum issuedAbstract readReview
In one paragraph

Review in Journal of orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. The silver tsunami and the elective arthroplasty crisis: How geriatric trauma overruns public surgical capacity.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Article
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  5. Article
  6. Article
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  8. Article
  9. Observational
  10. Article
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  15. Article
  16. Observational
  17. Analysis of the Associations between Arthritis and Fall Histories in Korean Adults.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Rehabilitation of falls in patients with iatrogenic chemotherapy-induced neuropathy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Giorgio di Laura FratturaOspedale Regionale di Lugano - EOC - Via Tesserete, 46 - Lugano, Switzerland.
Giuseppe FilardoRizzoli Orthopaedic Institute - Via Di Barbiano, 1/10 - Bologna, Italy.
Dario GiunchiOspedale Regionale di Lugano - EOC - Via Tesserete, 46 - Lugano, Switzerland.
Augusto FuscoNeuromotor Rehabilitation, CDC Salus Infirmorum, Via della Lucchina, 41 - 00135, Rome, Italy.
Stefano ZaffagniniII Orthopaedic and Traumatologic Clinic - Rizzoli Orthopaedic Institute - Via Di Barbiano, 1/10 -Via G. C. Pupilli, 1 - 40136, Bologna, Italy.
Christian CandrianOspedale Regionale di Lugano - EOC - Via Tesserete, 46 - Lugano, Switzerland.
Ospedale regionale di Lugano · CHIstituto Ortopedico Rizzoli · ITDon Carlo Gnocchi Foundation · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFalls occur frequently in patients with impaired ambulation and may dramatically affect the elderly population. Aim was to document the incidence of falls in knee osteoarthritis (OA) patients undergoing total knee arthroplasty (TKA), and to identify factors and treatments that may influence the risk of falls.

methodsA systematic literature search was conducted on three medical electronic databases, PubMed, PeDRO, and Cochrane Collaboration. The Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines were used. Risk of bias analysis and best evidence synthesis were performed. The main aspects related to falls were analyzed: prevalence, risk factors, correlation with clinical outcome, effect of treatments.

resultsThe systematic review identified 11 papers on 1237 patients. Pre-operative fall prevalence ranged from 23% to 63%, while post-operative values ranged from 12% to 38%. Moderate evidence was found on no influence of clinical scales, no BMI differences between "faller" and "non-faller", and on influence of limited pre-operative range of motion. Conflicting evidence was found for sex, history of previous falls, age, kyphosis, muscle weakness, fear of falling, depression, balance, gait impairment. No evidence was found for the effectiveness of surgical or rehabilitative strategies on falls reduction.

conclusionsOA patients undergoing TKA are at high risk of falls, which is reduced but still present after surgery. Although some risk factors were identified, there are no studies demonstrating the possibility of reducing the incidence of this deleterious event, which warrants further research efforts to better manage this fragile population of elderly patients.

Identifiers

PMID30174378
PMCPMC6115537
OpenAlexW2888270798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.