Evidence map›Paper›PMID 30174043›Full record

ArticleFood chemistry2019

Lemon yellow #15 a new highly stable, water soluble food colorant from the peel of Citrus limon.

Xiaoyan Chen, Yuanqing Ding, Billy Forrest, Joonseok Oh, Stephanie M Boussert, Mark T Hamann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Two natural products from the seeds ofFrontiers in pharmacology · 2025
    Article
  2. Antioxidant activities of premature and mature mandarin (Food science and biotechnology · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoyan ChenDepartment of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USA.
Yuanqing DingNational Center for Natural Products Research, Department of BioMolecular Sciences, Division of Pharmacognosy, and Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA.
Billy ForrestDivision of Pharmacognosy, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA.
Joonseok OhDivision of Pharmacognosy, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA.
Stephanie M BoussertDepartment of Chemistry and Biochemistry, College of Charleston, Charleston, SC 29401, USA.
Mark T HamannDepartment of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USA. Electronic address: hamannm@musc.edu.

Funding

SOURCING, ACQUISITION AND DATABASE COREP20RR021929 · NCRR · UNIVERSITY OF MISSISSIPPI · PI DOERKSEN, ROBERT J · 2006 to 2010
$11.1M
Natural Product HCV Drugs from Rare Plant-Microbe InteractionsR01AT007318 · NCCIH · UNIVERSITY OF MISSISSIPPI · PI HAMANN, MARK T · 2012 to 2016
$1.6M
NCCIH NIH HHS R01 AT007318NCRR NIH HHS P20 RR021929
6 · The paper itself

Abstract

To provide stable and low-cost naturally derived yellow pigments, a variety of food byproducts were evaluated and the constituents of lemon peel have emerged yielding a highly promising natural product with applications as a food dye. Here we report a new, highly stable and water soluble food dye called yellow #15 from the ethanol extract of the zest of Citrus limon. The structure of lemon yellow #15 was carefully assigned on the basis of spectroscopic data, including 1D and 2D NMR spectroscopy, and the absolute configuration was established by comparison of the experimental CD with calculated electronic circular dichroism (ECD) spectral data. CIELAB values and Delta CIELAB were measured and revealed this new water-soluble pigment has superior light stability relative to other natural products used as food dyes.

Indexed as

Food Coloring AgentsCitrusFoodPlant ExtractsWaterFood Coloring AgentsPlant ExtractsWater3-Hydroxy-3-methylglutaryl (HMG)Citrus limonFood colorantLemon yellow #15

Identifiers

PMID30174043
PMCPMC11192143

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.