Evidence map›Paper›PMID 30173888›Full record

ArticleBiophysical journal2018

NCX-Mediated Subcellular Ca

Mingwang Zhong, Colin M Rees, Dmitry Terentyev, Bum-Rak Choi, Gideon Koren, Alain Karma

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Variable expressivity in long QT syndrome type 2 rabbits defines a low threshold for therapeuticAmerican journal of physiology. Heart and circulatory physiology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Role of ryanodine receptor cooperativity in CaThe Journal of physiology · 2024
    Article
  6. Activation of small conductance CaThe Journal of physiology · 2023
    Article
  7. Review
  8. Improved CaJournal of molecular and cellular cardiology · 2022
    Article
  9. Review
  10. Article
  11. Late ICirculation. Arrhythmia and electrophysiology · 2020
    Article
  12. Arrhythmogenic late CaProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  13. Targeting CaFrontiers in physiology · 2020
    Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mingwang ZhongPhysics Department and Center for Interdisciplinary Research in Complex Systems, Northeastern University, Boston, Massachusetts.
Colin M ReesPhysics Department and Center for Interdisciplinary Research in Complex Systems, Northeastern University, Boston, Massachusetts.
Dmitry TerentyevCardiovascular Research Centre, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Bum-Rak ChoiCardiovascular Research Centre, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Gideon KorenCardiovascular Research Centre, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island.
Alain KarmaPhysics Department and Center for Interdisciplinary Research in Complex Systems, Northeastern University, Boston, Massachusetts. Electronic address: a.karma@neu.edu.
Northeastern University · USBrown University · USRhode Island Hospital · US

Funding

A Multi-Scale Approach to Cardiac Arrhythmia: from the Molecule to the OrganR01HL110791 · NHLBI · RHODE ISLAND HOSPITAL · PI KOREN, GIDEON · 2013 to 2017
$7.3M
HEART AND MUSCLE K+ CHANNELS--STRUCTURE AND FUNCTIONR01HL046005 · NHLBI · RHODE ISLAND HOSPITAL · PI KOREN, GIDEON · 1991 to 2013
$5.9M
REgulation of Calcium Homeostasis by MyomiRs in Heart FailureR01HL121796 · NHLBI · RHODE ISLAND HOSPITAL · PI TERENTYEV, DMITRY A · 2015 to 2019
$2.0M
NHLBI NIH HHS R01 HL046005NHLBI NIH HHS R01 HL110791NHLBI NIH HHS R01 HL121796
6 · The paper itself

Abstract

Long QT syndrome type 2 (LQT2) is a congenital disease characterized by loss of function mutations in hERG potassium channels (I

Indexed as

AnimalsCalciumCytosolHeart VentriclesIntracellular SpaceIon Channel GatingLong QT SyndromeModels, BiologicalMyocytes, CardiacPhenotypeProbabilityRabbitsRyanodine Receptor Calcium Release ChannelSodium-Calcium ExchangerCalciumRyanodine Receptor Calcium Release ChannelSodium-Calcium Exchanger

Identifiers

PMID30173888
PMCPMC6140381
OpenAlexW2887786112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.