ArticleThe Kaohsiung journal of medical sciences2018
Metabolic syndrome and vaspin in patients with bipolar disorder.
Article in The Kaohsiung journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 7 citations in OpenAlex.
- Association of the triglyceride-glucose index with inflammatory markers and dysregulation of adipokines in patients with metabolic syndrome.BMC endocrine disorders · 2026Article
- Serum Asprosin and Peptide Tyrosine Tyrosine (PYY) Levels in Bipolar Disorder.Journal of clinical medicine · 2025Article
- Prevalence and Pathogenic Factors of Thyroid Dysfunction in First-Episode and Drug-Naïve Major Depressive Disorder Patients With Fasting Blood Glucose Abnormalities in Early- and Late-Onset Age.Depression and anxiety · 2025Article
- Chitinase-3-like protein 1 levels in bipolar disorder.Saudi medical journal · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
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Abstract
Metabolic disorders and abnormal levels of circulating adipokines have been reported in patients with bipolar disorder (BD). The aim of this study was to investigate the differences in the correlations of vaspin plasma levels and metabolic parameters between two groups: patients with BD and mentally healthy persons. We measured plasma levels of vaspin, metabolic parameters, and metabolic syndrome (MS) in 101 patients with BD and 90 healthy control (HC) subjects. Patients with BD were evaluated with the Young Mania Rating Scale (YMRS) to assess manic symptoms and the Hamilton Depression Scale (HDS) to assess depressive symptoms. The Global Assessment of Functioning (GAF) was used to evaluate the general functions of the patients. Body mass index (BMI), weight, waist circumference (WC), fasting glucose, and triglyceride levels of the study group were statistically higher than those of the healthy controls (p = 0.001, p < 0.001, p < 0.001, p = 0.027, and p = 0.001 respectively). Plasma levels of vaspin were 0.978 ng/ml in patients with BD and 0.292 in the HC group (p < 0.001). Our study revealed associations between metabolic parameters/metabolic syndrome and vaspin plasma concentrations in patients with BD. Vaspin can play a specific role in the pathogenesis of metabolic disorders in these subjects and can be a specific indicator substance in BD.
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