Evidence map›Paper›PMID 30173502›Full record

ArticleInternational journal of stem cells2018

Improved Transfection Efficiency and Metabolic Activity in Human Embryonic Stem Cell Using Non-Enzymatic Method.

C-Yoon Kim, In-Kyu Hwang, Changhee Kang, Eun-Bin Chung, Cho-Rok Jung, Hanseul Oh, Young-Hoon Jeong, Sung-Hwan Moon, Jong Soo Kim, Ki-Sung Hong and 2 more

Open access · diamondAbstract read
In one paragraph

Article in International journal of stem cells, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

C-Yoon KimDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
In-Kyu HwangDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Changhee KangDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Eun-Bin ChungDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Cho-Rok JungGene Therapy Research Unit, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Hanseul OhDepartment of Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea.
Young-Hoon JeongDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Sung-Hwan MoonDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Jong Soo KimDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Ki-Sung HongDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Jae-Hak ParkDepartment of Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea.
Hyung-Min ChungDepartment of Stem Cell Biology, School of Medicine, Konkuk University, Seoul, Korea.
Konkuk University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human embryonic stem cells (hESCs) are pluripotent cells widely used in conventional and regenerative medicine due to their ability to self-renew, proliferate and differentiate. Recently, genetic modification of stem cells using genome editing is the most advanced technique for treating hereditary diseases. Nevertheless, the low transfection efficiency of hESCs using enzymatic methods is still limited in

Indexed as

EDTAHuman embryonic stem cellMetabolic activityTransfection

Identifiers

PMID30173502
PMCPMC6285293
OpenAlexW2890814494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.