Evidence map›Paper›PMID 30173298›Full record

SynthesisInternal and emergency medicine2019

Clinical effects of acute kidney injury after transcatheter aortic valve implantation: a systematic review and meta-analysis.

Min Ma, Wei-Dong Gao, Yun-Fei Gu, Yu-Shu Wang, Ye Zhu, Yong He

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Internal and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. A Novel Protocol for Contrast-Free Transcatheter Aortic Valve Replacement Evaluation and Implantation.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  11. Article
  12. Volume of contrast to creatinine clearance ratio predicts early mortality and AKI after TAVI.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min MaDepartment of Cardiology, The Sixth People's Hospital of Chengdu, Chengdu, 610051, China.
Wei-Dong GaoDepartment of Cardiology, Jiangmen Central Hospital, Jiangmen, 529030, Guangduo, China.
Yun-Fei GuDepartment of Cardiology, LuoYang Central Hospital Affiliated to ZhengZhou University, No 288 Zhongzhou Road, Luoyang, 471000, China.
Yu-Shu WangDepartment of Cardiology, The First People's Hospital of Chengdu, Chengdu, 610016, China.
Ye ZhuDepartment of Cardiology, West China Hospital, Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China.
Yong HeDepartment of Cardiology, West China Hospital, Sichuan University, No. 37 GuoXue Street, Chengdu, 610041, China. heyong_huaxi@163.com.

Funding

The Applied and Fundamental Study of Sichuan Province 2017JY0026
6 · The paper itself

Abstract

Several observational studies have shown that postoperative acute kidney injury (AKI) may significantly worsen the prognosis of a transcatheter aortic valve implantation (TAVI). The purpose of this systematic review and meta-analysis is to evaluate the recent evidence on the impact of AKI on clinical outcomes following TAVI. A comprehensive search in PubMed, Embase and the Cochrane Library was performed for relevant studies by two independent investigators. We pooled the odds ratio (OR) from individual studies, and performed heterogeneity, quality assessment and publication bias analysis. Forty-three eligible studies comprising 544,112 patients were included. Postoperative AKI not only significantly increased the risk for short-term and long-term all-cause mortality (OR 6.25, 95% CI 5.72-6.83, P < 0.00001; OR 3.49, 95% CI 2.78-4.40, P < 0.00001, respectively), but also increased the risk for early myocardial infarction (OR 3.98, 95% CI 1.90-8.31, P = 0.0002), major and life-threatening bleeding (OR 1.51, 95% CI 1.12-2.03, P = 0.007; OR 2.35, 95% CI 1.80-3.06, P < 0.00001, respectively), major vascular complications (OR 1.69, 95% CI 1.30-2.18, P < 0.0001), need for blood transfusion (OR 2.15, 95% CI 1.89-2.46, P < 0.00001) renal replacement therapy (OR 22.36, 95% CI 11.88-42.12, P = 0.0002) and cerebrovascular accidents (OR 1.92, 95% CI 1.23-2.98, P = 0.004). Acute kidney injury following TAVI is associated with increased postoperative mortality and morbidity. Future efforts are required to determine whether early prevention of post-procedural AKI after TAVI impacts upon clinical outcomes.

Indexed as

Acute Kidney InjuryPostoperative ComplicationsTranscatheter Aortic Valve ReplacementHemorrhageHumansMyocardial InfarctionObservational Studies as TopicPrognosisRisk FactorsAcute kidney injuryMeta-analysisMorbidityMortalityTranscatheter aortic valve implantation

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.