ArticleMedical science monitor : international medical journal of experimental and clinical research2018
Use of Apparent Diffusion Coefficient Histogram in Differentiating Between Medulloblastoma and Pilocytic Astrocytoma in Children.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Paediatric thalamic tumours: a predictive MR phenotype.Neuroradiology · 2026Article
- Fusion of habitat analysis and deep learning on contrast-enhanced T1-weighted imaging for predicting Ki-67 status in pediatric brain tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Whole-lesion iodine map histogram analysis in the risk classification of gastrointestinal stromal tumors: comparison with single-slice iodine concentration measurements.Abdominal radiology (New York) · 2024Article
- Benign Glioma.Advances in experimental medicine and biology · 2023Article
- The Diagnostic Efficiency of Quantitative Diffusion Weighted Imaging in Differentiating Medulloblastoma from Posterior Fossa Tumors: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2022Review
- Article
- Apparent Diffusion Coefficient Histogram Analysis for the Preoperative Evaluation of Ki-67 Expression in Pituitary Macroadenoma.Clinical neuroradiology · 2022Article
- An analysis of Ki-67 expression in stage 1 invasive ductal breast carcinoma using apparent diffusion coefficient histograms.Quantitative imaging in medicine and surgery · 2021Article
- Advancements in Neuroimaging to Unravel Biological and Molecular Features of Brain Tumors.Cancers · 2021Review
- Solid Indeterminate Nodules with a Radiological Stability Suggesting Benignity: A Texture Analysis of Computed Tomography Images Based on the Kurtosis and Skewness of the Nodule Volume Density Histogram.Pulmonary medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND This research aimed to investigate the value of apparent diffusion coefficient (ADC) histogram in differentiating between medulloblastoma and pilocytic astrocytoma in children. MATERIAL AND METHODS Thirty-three children with posterior cranial fossa tumor confirmed by operation and pathology participated in this retrospective study, including 18 children with medulloblastoma and 15 children with pilocytic astrocytoma. ADC images of the maximum lay of tumors were selected, and the region of interest was delineated by Mazda software and analyzed by histogram. Histogram characteristic parameters of the 2 tumors were statistically analyzed to determine the significantly different characteristic parameters between the 2 tumor types. RESULTS There were significant differences in the mean value, variance, skewness, kurtosis, and 1th, 10th, 50th, and 90th percentiles of 9 characteristic parameters extracted by histogram (P<0.05). The corresponding receiver operating characteristic (ROC) curves were drawn, in which the mean value and 50th percentile were best identified. When the maximum area under the ROC curve was 1 and the optimal threshold was 137.7 and 125.5, the specificity and sensitivity were both 100%. CONCLUSIONS ADC histograms can be used to differentiate between medulloblastoma and pilocytic astrocytoma in children and provide reliable and objective evidence for the differentiation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.