Evidence map›Paper›PMID 30173171›Full record

ArticleAmerican journal of critical care : an official publication, American Association of Critical-Care Nurses2018

Advancing In-Hospital Clinical Deterioration Prediction Models.

Alvin D Jeffery, Mary S Dietrich, Daniel Fabbri, Betsy Kennedy, Laurie L Novak, Joseph Coco, Lorraine C Mion

Abstract readComparative Study
In one paragraph

Article in American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alvin D JefferyAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio. alvinjeffery@gmail.com.
Mary S DietrichAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio.
Daniel FabbriAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio.
Betsy KennedyAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio.
Laurie L NovakAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio.
Joseph CocoAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio.
Lorraine C MionAlvin D. Jeffery is a medical informatics fellow at the US Department of Veterans Affairs, Tennessee Valley Health-care System, Nashville, Tennessee, and a postdoctoral research fellow, Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee. Mary S. Dietrich is a professor of statistics and measurement, Schools of Medicine (Biostatistics, Vanderbilt-Ingram Cancer Center, Psychiatry) and Nursing, Vanderbilt University. Daniel Fabbri is an assistant professor, Department of Biomedical Informatics, Vanderbilt University. Betsy Kennedy is a professor, School of Nursing, Vanderbilt University. Laurie L. Novak is an assistant professor and Joseph Coco is a senior application developer, Department of Biomedical Informatics, Vanderbilt University. Lorraine C. Mion is a professor, College of Nursing, The Ohio State University, Columbus, Ohio.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR002243
6 · The paper itself

Abstract

backgroundEarly warning systems lack robust evidence that they improve patients' outcomes, possibly because of their limitation of predicting binary rather than time-to-event outcomes.

objectivesTo compare the prediction accuracy of 2 statistical modeling strategies (logistic regression and Cox proportional hazards regression) and 2 machine learning strategies (random forest and random survival forest) for in-hospital cardiopulmonary arrest.

methodsRetrospective cohort study with prediction model development from deidentified electronic health records at an urban academic medical center.

resultsThe classification models (logistic regression and random forest) had statistical recall and precision similar to or greater than those of the time-to-event models (Cox proportional hazards regression and random survival forest). However, the time-to-event models provided predictions that could potentially better indicate to clinicians whether and when a patient is likely to experience cardiopulmonary arrest.

conclusionsAs early warning scoring systems are refined, they must use the best analytical methods that both model the underlying phenomenon and provide an understandable prediction.

Indexed as

Clinical DeteriorationMachine LearningModels, StatisticalAcademic Medical CentersCohort StudiesCritical CareHeart ArrestHumansRetrospective Studies

Identifiers

PMID30173171
PMCPMC6141236

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.