ArticleAcademic radiology2019
Contrast-to-Noise Ratio Optimization in Coronary Computed Tomography Angiography: Validation in a Swine Model.
Article in Academic radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Optimising Generalisable Deep Learning Models for CT Coronary Segmentation: A Multifactorial Evaluation.Journal of imaging informatics in medicine · 2026Article
- Automatic Quantification of Local Plaque Thickness Differences as Assessed by Serial Coronary Computed Tomography Angiography Using Scan-Quality-Based Vessel-Specific Thresholds.Cardiology and therapy · 2024Article
- Low-dose quantitative CT myocardial flow measurement using a single volume scan: phantom and animal validation.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- CT Evaluation of the Tracheobronchial Tree in Swine.Comparative medicine · 2023Article
- Dynamic CT myocardial perfusion without image registration.Scientific reports · 2022Article
- Contrast timing optimization of a two-volume dynamic CT pulmonary perfusion technique.Scientific reports · 2022Article
- Combining perfusion and angiography with a low-dose cardiac CT technique: a preliminary investigation in a swine model.The international journal of cardiovascular imaging · 2021Article
- Dynamic pulmonary CT perfusion using first-pass analysis technique with only two volume scans: Validation in a swine model.PloS one · 2020Article
- Low-Radiation-Dose Stress Myocardial Perfusion Measurement Using First-Pass Analysis Dynamic Computed Tomography: A Preliminary Investigation in a Swine Model.Investigative radiology · 2019Article
- Timing optimization of low-dose first-pass analysis dynamic CT myocardial perfusion measurement: validation in a swine model.European radiology experimental · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
RATIONALE AND
objectivesThe accuracy of coronary computed tomography (CT) angiography depends upon the degree of coronary enhancement as compared to the background noise. Unfortunately, coronary contrast-to-noise ratio (CNR) optimization is difficult on a patient-specific basis. Hence, the objective of this study was to validate a new combined diluted test bolus and CT angiography protocol for improved coronary enhancement and CNR. MATERIALS AND
methodsThe combined diluted test bolus and CT angiography protocol was validated in six swine (28.9 ± 2.7 kg). Specifically, the aortic and coronary enhancement and CNR of a standard CT angiography protocol, and a new combined diluted test bolus and CT angiography protocol were compared to a reference retrospective CT angiography protocol. Comparisons for all data were made using box plots, t tests, regression, Bland-Altman, root-mean-square error and deviation, as well as Lin's concordance correlation.
resultsThe combined diluted test bolus and CT angiography protocol was found to improve aortic and coronary enhancement by 26% and 13%, respectively, as compared to the standard CT angiography protocol. More importantly, the combined protocol was found to improve aortic and coronary CNR by 29% and 20%, respectively, as compared to the standard protocol.
conclusionA new combined diluted test bolus and CT angiography protocol was shown to improve coronary enhancement and CNR as compared to an existing standard CT angiography protocol.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.