Evidence map›Paper›PMID 30172187›Full record

ArticlePsychiatry research2018

Childhood malnutrition and maltreatment are linked with personality disorder symptoms in adulthood: Results from a Barbados lifespan cohort.

Rebecca S Hock, Cyralene P Bryce, Laura Fischer, Michael B First, Garrett M Fitzmaurice, Paul T Costa, Janina R Galler

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PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Rebecca S HockThe Chester M. Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: rhock@mgh.harvard.edu.
Cyralene P BryceHarvard Medical School, Boston, MA, USA; Barbados Nutrition Study, Bridgetown, Barbados.
Laura FischerChildren's National Medical Center, Washington, DC, USA.
Michael B FirstDepartment of Psychiatry, Columbia University, New York, NY, USA.
Garrett M FitzmauriceMcLean Hospital, Belmont, MA, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Paul T CostaBehavioral Medicine Research Center, Department of Psychiatry and Behavioral Science, Duke University School of Medicine, Durham, NC, USA.
Janina R GallerThe Chester M. Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Center on the Developing Child, Harvard University, Cambridge, MA, USA.
Harvard University · USChildren's National · USColumbia University · USDuke University · USMassachusetts General Hospital · USMcLean Hospital · US

Funding

Transgenerational Effects of Undernutrition on ChildrenR01HD060986 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI GALLER, JANINA R. · 2011 to 2015
$4.9M
The MGH Global Psychiatric Clinical Research Training ProgramT32MH093310 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FRICCHIONE, GREGORY L, HENDERSON, DAVID C · 2012 to 2016
$1.3M
NICHD NIH HHS R01 HD060986NIMH NIH HHS T32 MH093310
6 · The paper itself

Abstract

Both childhood malnutrition and maltreatment are associated with mental health problems that can persist into adulthood. Previously we reported that in Barbados, those with a history of infant malnutrition were more likely to report having experienced childhood maltreatment. Few studies, however, address the long-term outcomes of those who have been exposed to both. We assessed the unique and combined associations of a history of early malnutrition and childhood maltreatment with personality pathology in mid-adulthood in participants of the 47-year longitudinal Barbados Nutrition Study. We used the Structured Clinical Interview for DSM-IV-TR Axis II Personality Disorders Personality Questionnaire (SCID-II-PQ) and NEO Personality Inventory-Revised derived Five-Factor Model (NEO PI-R FFM) personality disorder (PD) scores to assess personality pathology, the Childhood Trauma Questionnaire-Short Form (CTQ-SF) to assess childhood maltreatment, and clinical documentation of malnutrition in infancy. We tested the associations of malnutrition and maltreatment with PD scores using linear regression models, unadjusted and adjusted for other childhood adversities. We found increased scores for paranoid, schizoid, avoidant, and dependent PDs among those who had been malnourished and increased scores for paranoid, schizoid, schizotypal, and avoidant PDs among those with higher childhood maltreatment scores. Overall, those exposed to both adversities had even greater PD scores.

Indexed as

AdultAdult Survivors of Child AbuseBarbadosChildChild AbuseFemaleHumansMaleMalnutritionPersonality DisordersSurveys and QuestionnairesCaribbeanChild abuseCTQEarly adversityEarly life stressNutrition

Identifiers

PMID30172187
PMCPMC6267931
OpenAlexW2808888245

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.