Evidence map›Paper›PMID 30171621›Full record

SynthesisJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2019

Diagnostic Accuracy of 2-Dimensional Shear Wave Elastography for the Staging of Liver Fibrosis: A Meta-analysis.

Wei Zhang, Ya Zhu, Cuncheng Zhang, Haitao Ran

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Imaging Evaluation for Steatotic Liver Disease.Korean journal of radiology · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Clinical Significance of Liver MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2023
    Review
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wei ZhangInstitute of Ultrasound Imaging and Department of Ultrasound, Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing, China.
Ya ZhuDepartment of Obstetrics and Gynecology, Dong Feng Affiliated Hospital, Hubei University of Medicine, Shiyan, China.
Cuncheng ZhangInstitute of Ultrasound Imaging and Department of Ultrasound, Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing, China.
Haitao RanInstitute of Ultrasound Imaging and Department of Ultrasound, Second Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ultrasound Molecular Imaging, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the overall accuracy of 2-dimensional shear wave elastography (SWE) for the staging of liver fibrosis.

methodsLiterature databases and conference abstracts were searched from 2000 to September 2017. Sensitivity, specificity, and other information were extracted from the included studies. Methodological quality was assessed with Quality Assessment of Diagnostic Accuracy Studies 2 tools. Data were synthesized by a bivariate hierarchical model.

resultsThe summary sensitivity and specificity were 0.85 (95% confidence interval [CI], 0.80-0.89) and 0.79 (95% CI, 0.72-0.85) for fibrosis stage F≥2, 0.90 (95% CI, 0.87-0.93) and 0.85 (95% CI, 0.80-0.89) for F≥3, and 0.89 (95% CI, 0.84-0.93) and 0.92 (95% CI, 0.89-0.95) for F=4, respectively. The areas under the summary receiver operating characteristic curve for F≥2, F≥3, and F=4 was 0.81, 0.77, and 0.84.

conclusionsTwo-dimensional SWE is a good noninvasive method for the diagnosis of substantial liver fibrosis and cirrhosis. Further studies are needed to assess severe fibrosis and to perform head-to-head comparisons of 2-dimensional SWE and other imaging modalities for the evaluation of liver fibrosis.

Indexed as

Databases, FactualElasticity Imaging TechniquesHumansLiverLiver CirrhosisReproducibility of ResultsSensitivity and SpecificitySeverity of Illness Index2-dimensional shear wave elastographyfibrosis stagingliver fibrosismeta-analysis

Identifiers

PMID30171621
PMCPMC7379518

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.