ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020
The clinical usefulness of phase analysis in detecting coronary artery disease using dipyridamole thallium-201-gated myocardial perfusion imaging with a cadmium-zinc-telluride camera.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Assessing the diagnostic value of left ventricular synchrony indices derived from phase analysis by D-SPECT in identifying obstructive coronary artery disease.The international journal of cardiovascular imaging · 2024Article
- Article
- Relationship between left ventricular mechanical synchrony and left ventricular systolic function: a CZT-SPECT analysis.BMC cardiovascular disorders · 2022Article
- Left ventricular mechanical dyssynchrony for CAD diagnosis: Does it have incremental clinical values?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- The clinical value and safety of ECG-gated dipyridamole myocardial perfusion imaging in patients with aortic stenosis.Scientific reports · 2019Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have demonstrated left ventricular mechanical dyssynchrony (LVMD) in patients with severe coronary artery disease (CAD) with ≥ 70% stenosis. The aim of this study was to evaluate the clinical usefulness of stress/rest LVMD in the diagnosis of CAD with ≥ 50% stenosis using dipyridamole thallium-201 (Tl-201) myocardial perfusion imaging (MPI) with a cadmium-zinc-telluride camera. METHODS AND
resultsA total of 476 patients without known CAD who underwent dipyridamole Tl-201 MPI and coronary angiography within 6 months were retrospectively reviewed. LVMD parameters including phase standard deviation and phase histogram bandwidth, phase skewness and phase kurtosis, as well as myocardial perfusion and myocardial stunning were assessed in post-stress and rest MPI. Relationships between the presence of CAD on coronary angiography and single photon emission computerized tomography (SPECT) parameters were evaluated. The presence of perfusion abnormalities was the best diagnostic tool in detecting CAD. Although less left ventricular synchrony was observed post-stress in the CAD group compared to the non-CAD group, no significant dyssynchrony was noted.
conclusionsThe addition of phase analysis to help diagnose CAD in Tl-201-gated SPECT with dipyridamole stress may have limited value in patients with CAD with ≥ 50% stenosis.
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